{"product_id":"abcam-ab279341","title":"Abcam, ab279341, Anti-IFFO1 antibody [EPR22711-61] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal IFFO1 antibody. Carrier free. Suitable for IP, WB and reacts with Human samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR22711-61,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WB, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab279341 is the carrier-free version of\u003cbr\u003e\nab242130\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nIFFO1 also known as Intermediate Filament Family Orphan 1 is a protein that plays a role in structural support in cells. It weighs approximately 63 kDa. IFFO1 is expressed in various tissues with a higher concentration in the heart and skeletal muscles and also found in the liver and testis. This target is involved in maintaining the integrity of the cytoskeleton by interacting with other cytoskeletal proteins.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe protein supports cellular architecture and dynamics during cell division and differentiation. IFFO1 can interact with other intermediate filament proteins but researchers suggest it may also function independently. Though not very well-studied it contributes to the stability of cells' mechanical properties playing a part in maintaining cellular organization and providing resilience against mechanical stress.\u003cbr\u003e\nPathways\u003cbr\u003e\nIts involvement in cytoskeletal organization connects it with the cytoskeletal remodeling pathway which is fundamental for cellular shape and stability. It associates with proteins like vimentin and desmin which are important in this pathway. These interactions underline its contribution to cell structure and mechanics connecting it to both cellular movement and morphological changes.\u003cbr\u003e\nEvidence links IFFO1 to muscular dystrophy where muscle integrity and function diminish and perhaps to certain liver conditions. The protein interacts with key structural entities like desmin which is also implicated in these disorders. Dysregulation of IFFO1 or its interacting partners may contribute to the disruption of muscle and liver function leading to progressive muscle disorders or hepatic pathologies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46856303804585,"sku":"ab279341","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab279341","provider":"Iright","version":"1.0","type":"link"}