{"product_id":"abcam-ab282421","title":"Abcam, ab282421, PRL-3 Inhibitor I","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 485.2 Da, Purity 98%. A potent inhibitor of PRL-3, IC 50 =0.9 μM. Sensitizes PRL-3-expressing cancer cells to chemotherapeutics. Inhibits dephosphorylation of tyrosine-783 of integrin β1 in BGC823 and SW480 cells. Reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:485.2 Da,\u003cbr\u003e\nMolecular formula:C17H11Br2NO2S2,\u003cbr\u003e\nPubChem:73707371,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO (up to 40 mg\/ml),\u003cbr\u003e\nBiochemical name:5-[[5-Bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone,\u003cbr\u003e\nBiological description:A potent inhibitor of PRL-3, IC50=0.9 μM. Sensitizes PRL-3-expressing cancer cells to chemotherapeutics. Inhibits dephosphorylation of tyrosine-783 of integrin β1 in BGC823 and SW480 cells. Reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model.,\u003cbr\u003e\nCanonical smiles:C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)C=C3C(=O)NC(=S)S3)Br,\u003cbr\u003e\nIsomeric smiles:C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)\/C=C\/3\\C(=O)NC(=S)S3)Br,\u003cbr\u003e\nInChi:InChI=1S\/C17H11Br2NO2S2\/c18-12-5-6-14(22-9-10-3-1-2-4-13(10)19)11(7-12)8-15-16(21)20-17(23)24-15\/h1-8H,9H2,(H,20,21,23)\/b15-8+,\u003cbr\u003e\nInChiKey:HXNBAOLVPAWYLT-OVCLIPMQSA-N,\u003cbr\u003e\nIUPAC Name:(5E)-5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nSolutions in DMSO may be stored at -20°C for up to 2 months.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Ambient - Cannot Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847428526249,"sku":"ab282421","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab282421","provider":"Iright","version":"1.0","type":"link"}