{"product_id":"abcam-ab282590","title":"Abcam, ab282590, Anti-MAGEA10 antibody [EPR24366-89] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal MAGEA10 antibody. Carrier free. Suitable for ICC\/IF, IP, Flow Cyt (Intra), WB, IHC-P and reacts with Human samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR24366-89,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:Flow Cyt (Intra), WB, IHC-P, ICC\/IF, IPSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab282590 is the carrier-free version of\u003cbr\u003e\nab271057\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nMAGEA10 also known as Melanoma Antigen Family A 10 is a member of the MAGE (Melanoma Antigen Gene) family. This protein has a molecular mass of about 36 kDa. MAGEA10 is expressed in various tumor cells and some male germline cells in the testis but not in normal somatic tissues. The expression pattern makes it an interesting target for cancer research and potential therapeutic interventions.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe function of MAGEA10 remains not fully understood but it likely plays a role in cell proliferation and survival. It is not a component of any known protein complex. Research suggests that MAGEA10 might modulate cellular processes by interacting with other proteins impacting pathways related to oncogenesis and cell cycle regulation.\u003cbr\u003e\nPathways\u003cbr\u003e\nMAGEA10 appears to be involved in critical pathways associated with cancer progression and possibly immune evasion. It interacts with proteins involved in cell signaling pathways such as the p53 pathway which is pivotal in regulating the cell cycle and apoptosis. MAGEA10 may influence these pathways by affecting gene transcription and modulating protein-protein interactions.\u003cbr\u003e\nMAGEA10 has a strong connection to cancer particularly in melanoma and lung cancer. Overexpression of MAGEA10 in these cancers suggests a possible role in tumor growth and metastasis. The protein is part of cancer-testis antigens similar to MAGEA1 another member of the same family implicated in various malignancies suggesting that targeting MAGEA10 could aid in developing specific cancer immunotherapies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46860445024425,"sku":"ab282590","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab282590","provider":"Iright","version":"1.0","type":"link"}