{"product_id":"abcam-ab286986","title":"Abcam, ab286986, Genz-123346","description":"\u003cp\u003eSize: 10mg \/ 50mg\u003cbr\u003e\nMW 418.6 Da, Purity \u0026gt;98%. Potent and selective glucosylceramide synthase inhibitor with potential anticancer activity.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:491833-30-8,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:418.6 Da,\u003cbr\u003e\nMolecular formula:C24H38N2O4,\u003cbr\u003e\nPubChem:23652732,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:DMSO,\u003cbr\u003e\nBiochemical name:Genz-123346 free base,\u003cbr\u003e\nBiological description:Potent and selective glucosylceramide synthase inhibitor with potential anticancer activity.Does not affect the activities of other related glycosidase, such as 1-Oacylceramide synthase, a-glucosidase, and glucocerebrosidase in any significant manner.Shown to improve glucose tolerance, improve insulin sensitivity, and normalize hemoglobin A1C levels in Zucker diabetic fatty rats.,\u003cbr\u003e\nCanonical smiles:CCCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O,\u003cbr\u003e\nIsomeric smiles:CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O,\u003cbr\u003e\nInChi:InChI=1S\/C24H38N2O4\/c1-2-3-4-5-6-7-10-23(27)25-20(18-26-13-8-9-14-26)24(28)19-11-12-21-22(17-19)30-16-15-29-21\/h11-12,17,20,24,28H,2-10,13-16,18H2,1H3,(H,25,27)\/t20-,24-\/m1\/s1,\u003cbr\u003e\nInChiKey:JMNXWOFCUJJYEO-HYBUGGRVSA-N,\u003cbr\u003e\nIUPAC Name:N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]nonanamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2286 genz-123346. B2286-10 is the same size as the 10 mg size of ab286986.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847498715305,"sku":"ab286986","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab286986","provider":"Iright","version":"1.0","type":"link"}