{"product_id":"abcam-ab286999","title":"Abcam, ab286999, ML-162","description":"\u003cp\u003eSize: 1mg \/ 5mg\u003cbr\u003e\nMW 477.4 Da, Purity \u0026gt;98%. ML-162 is a GPX4 (glutathione peroxidase 4) inhibitor that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC₅₀s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1035072-16-2,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:477.4 Da,\u003cbr\u003e\nMolecular formula:C23H22Cl2N2O3S,\u003cbr\u003e\nPubChem:3689413,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to \u0026gt;25 mM,\u003cbr\u003e\nBiochemical name:2-[(chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide,\u003cbr\u003e\nBiological description:ML-162 is a GPX4 (glutathione peroxidase 4) inhibitor that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC₅₀s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).,\u003cbr\u003e\nCanonical smiles:COC1=C(C=C(C=C1)N(C(C2=CC=CS2)C(=O)NCCC3=CC=CC=C3)C(=O)CCl)Cl,\u003cbr\u003e\nInChi:InChI=1S\/C23H22Cl2N2O3S\/c1-30-19-10-9-17(14-18(19)25)27(21(28)15-24)22(20-8-5-13-31-20)23(29)26-12-11-16-6-3-2-4-7-16\/h2-10,13-14,22H,11-12,15H2,1H3,(H,26,29),\u003cbr\u003e\nInChiKey:UNVKYJSNMVDZJE-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2304 ML-162. B2304-5 is the same size as the 5 mg size of ab286999.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847502581929,"sku":"ab286999","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab286999","provider":"Iright","version":"1.0","type":"link"}