{"product_id":"abcam-ab287027","title":"Abcam, ab287027, BI-409306 (Osoresnontrine)","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 311.34 Da, Purity \u0026gt;98%. BI-409306 is a potent and selective PDE9A inhibitor (IC50 = 52 nM). Displays weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 \u0026gt; 10 μM). Potentially could be useful for the treatment of Alzheimer's disease and Schizophrenia.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1189767-28-9,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:311.34 Da,\u003cbr\u003e\nMolecular formula:C16H17N5O2,\u003cbr\u003e\nPubChem:135908617,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to \u0026gt;100 mM,\u003cbr\u003e\nBiochemical name:Osoresnontrine,\u003cbr\u003e\nBiological description:BI-409306 is a potent and selective PDE9A inhibitor (IC50 = 52 nM). Displays weak activity against other PDEs, such as PDE1A (IC50, 1.4 μM), PDE1C (IC50, 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A (IC50 \u0026gt; 10 μM). Potentially could be useful for the treatment of Alzheimer's disease and Schizophrenia.,\u003cbr\u003e\nCanonical smiles:C1COCCC1N2C3=C(C=N2)C(=O)NC(=N3)CC4=CC=CC=N4,\u003cbr\u003e\nInChi:InChI=1S\/C16H17N5O2\/c22-16-13-10-18-21(12-4-7-23-8-5-12)15(13)19-14(20-16)9-11-3-1-2-6-17-11\/h1-3,6,10,12H,4-5,7-9H2,(H,19,20,22),\u003cbr\u003e\nInChiKey:BZTIJCSHNVZMES-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:1-(oxan-4-yl)-6-(pyridin-2-ylmethyl)-5H-pyrazolo[3,4-d]pyrimidin-4-one\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2377 BI-409306. B2377-25 is the same size as the 25 mg size of ab287027.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847497633961,"sku":"ab287027","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab287027","provider":"Iright","version":"1.0","type":"link"}