{"product_id":"abcam-ab287028","title":"Abcam, ab287028, IITZ-01","description":"\u003cp\u003eSize: 1mg\u003cbr\u003e\nMW 482.5 Da, Purity \u0026gt;98%. IITZ-01 (ab287028) is a potent lysosomotropic autophagy inhibitor; displays \u0026gt;10-fold potent autophagy inhibition than Chloroquine; enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:1807988-47-1,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:482.5 Da,\u003cbr\u003e\nMolecular formula:C26H23FN8O,\u003cbr\u003e\nPubChem:134817273,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:Soluble in DMSO to \u0026gt;100 mM,\u003cbr\u003e\nBiochemical name:CID 134817273,\u003cbr\u003e\nBiological description:IITZ-01 (ab287028) is a potent lysosomotropic autophagy inhibitor; displays \u0026gt;10-fold potent autophagy inhibition than Chloroquine; enhances autophagosome accumulation but inhibits autophagosomal degradation by impairing lysosomal function, finally resulting in the inhibition of autophagy. Displays potent anticancer activity.,\u003cbr\u003e\nCanonical smiles:C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)F)NC4=CC=C(C=C4)C5=NC6=CC=CC=C6N5,\u003cbr\u003e\nInChi:InChI=1S\/C26H23FN8O\/c27-18-7-11-20(12-8-18)29-25-32-24(33-26(34-25)35-13-15-36-16-14-35)28-19-9-5-17(6-10-19)23-30-21-3-1-2-4-22(21)31-23\/h1-12H,13-16H2,(H,30,31)(H2,28,29,32,33,34),\u003cbr\u003e\nInChiKey:XGEDDGLPNSLBFE-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:4-N-[4-(1H-benzimidazol-2-yl)phenyl]-2-N-(4-fluorophenyl)-6-morpholin-4-yl-1,3,5-triazine-2,4-diamine\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2378 IITZ-01. B2378-5 is the same size as the 5 mg size of ab287028.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847503564969,"sku":"ab287028","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab287028","provider":"Iright","version":"1.0","type":"link"}