{"product_id":"abcam-ab287106","title":"Abcam, ab287106, E7820","description":"\u003cp\u003eSize: 5mg \/ 25mg\u003cbr\u003e\nMW 336.4 Da, Purity \u0026gt;98%. A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:289483-69-8,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:336.4 Da,\u003cbr\u003e\nMolecular formula:C17H12N4O2S,\u003cbr\u003e\nPubChem:196970,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:\u0026gt;30 mg\/ml in DMSO,\u003cbr\u003e\nBiochemical name:N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide,\u003cbr\u003e\nBiological description:A small molecule sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.,\u003cbr\u003e\nCanonical smiles:CC1=C2C(=CNC2=C(C=C1)NS(=O)(=O)C3=CC=CC(=C3)C#N)C#N,\u003cbr\u003e\nInChi:InChI=1S\/C17H12N4O2S\/c1-11-5-6-15(17-16(11)13(9-19)10-20-17)21-24(22,23)14-4-2-3-12(7-14)8-18\/h2-7,10,20-21H,1H3,\u003cbr\u003e\nInChiKey:LWGUASZLXHYWIV-UHFFFAOYSA-N,\u003cbr\u003e\nIUPAC Name:3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2600 E7820. B2600-25 is the same size as the 25 mg size of ab287106.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847442976937,"sku":"ab287106","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab287106","provider":"Iright","version":"1.0","type":"link"}