{"product_id":"abcam-ab287122","title":"Abcam, ab287122, LF3","description":"\u003cp\u003eSize: 5mg\u003cbr\u003e\nMW 416.6 Da, Purity \u0026gt;98%. A potent inhibitor of canonical Wnt signaling pathway (IC 50  \u0026lt; 2 μM ). It can disrupt the interaction between catenin and TCF4. LF3 blocks the expression of a series of Wnt target genes in Wnt-addicted colon cancer cells. It inhibits proliferation of Wnt-addicted colon cancer cells through induction of cell-cycle arrest and also inhibits self-renewal capacity of cancer stem cells (CSCs).\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:664969-54-4,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:SolidSee storage information,\u003cbr\u003e\nMolecular weight:416.6 Da,\u003cbr\u003e\nMolecular formula:C20H24N4O2S2,\u003cbr\u003e\nPubChem:1213452,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nSolubility:\u0026gt;50 mg\/ml DMSO,\u003cbr\u003e\nBiochemical name:4-[(2E)-3-phenylprop-2-en-1-yl]-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide,\u003cbr\u003e\nBiological description:A potent inhibitor of canonical Wnt signaling pathway (IC50 \u0026lt; 2 μM ). It can disrupt the interaction between catenin and TCF4. LF3 blocks the expression of a series of Wnt target genes in Wnt-addicted colon cancer cells. It inhibits proliferation of Wnt-addicted colon cancer cells through induction of cell-cycle arrest and also inhibits self-renewal capacity of cancer stem cells (CSCs).,\u003cbr\u003e\nCanonical smiles:C1CN(CCN1CC=CC2=CC=CC=C2)C(=S)NC3=CC=C(C=C3)S(=O)(=O)N,\u003cbr\u003e\nIsomeric smiles:C1CN(CCN1C\/C=C\/C2=CC=CC=C2)C(=S)NC3=CC=C(C=C3)S(=O)(=O)N,\u003cbr\u003e\nInChi:InChI=1S\/C20H24N4O2S2\/c21-28(25,26)19-10-8-18(9-11-19)22-20(27)24-15-13-23(14-16-24)12-4-7-17-5-2-1-3-6-17\/h1-11H,12-16H2,(H,22,27)(H2,21,25,26)\/b7-4+,\u003cbr\u003e\nInChiKey:ZUQIFHLBPBLRRM-QPJJXVBHSA-N,\u003cbr\u003e\nIUPAC Name:4-[(E)-3-phenylprop-2-enyl]-N-(4-sulfamoylphenyl)piperazine-1-carbothioamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nThis product is manufactured by BioVision, an Abcam company and was previously called B2644 LF3. B2644-25 is the same size as the 25 mg size of ab287122.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847442485417,"sku":"ab287122","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab287122","provider":"Iright","version":"1.0","type":"link"}