{"product_id":"abcam-ab289849","title":"Abcam, ab289849, PD-0325901, Sterile-Filtered","description":"\u003cp\u003eSize: 1mL\u003cbr\u003e\nPD-0325901 (ab289849) is a selective and ATP non-competitive MEK1\/2 inhibitor that suppresses phosphorylation of ERK in murine colon 26 tumors (IC50 = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells.\u003cbr\u003e\nKey facts\u003cbr\u003e\nCAS number:391210-10-9,\u003cbr\u003e\nPurity:\u0026gt;98%,\u003cbr\u003e\nForm:LiquidSee storage information,\u003cbr\u003e\nMolecular weight:482.19 g\/mol,\u003cbr\u003e\nMolecular formula:C16H14F3IN2O4,\u003cbr\u003e\nNature:Synthetic,\u003cbr\u003e\nBiological description:Selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC50 = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells.,\u003cbr\u003e\nCanonical smiles:C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O,\u003cbr\u003e\nInChi:InChI=1S\/C16H14F3IN2O4\/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18\/h1-5,9,21,23-24H,6-7H2,(H,22,25)\/t9-\/m1\/s1,\u003cbr\u003e\nInChiKey:SUDAHWBOROXANE-SECBINFHSA-N,\u003cbr\u003e\nIUPAC Name:N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\n5mM sterile-filtered solution in DMSO.\u003cbr\u003e\nCheck out our range of MEK inhibitor biochemicals\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46847499960489,"sku":"ab289849","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab289849","provider":"Iright","version":"1.0","type":"link"}