{"product_id":"abcam-ab316974","title":"Abcam, ab316974, Anti-Pseudomonas Outer membrane porin F antibody [EPR28629-91] - BSA and Azide free","description":"\u003cp\u003eSize: 100µg \/ 1mg\u003cbr\u003e\nRabbit Recombinant Monoclonal ompF antibody. Carrier free. Suitable for WB, ICC\/IF, Flow Cyt (Intra), IP, I-ELISA, IHC-P and reacts with Transfected cell lysate - Pseudomonas aeruginosa, Transfected cell line - Pseudomonas aeruginosa, Recombinant full length protein - Pseudomonas aeruginosa samples.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Monoclonal,\u003cbr\u003e\nClone number:EPR28629-91,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Pseudomonas aeruginosa,\u003cbr\u003e\nApplications:Flow Cyt (Intra), IHC-P, I-ELISA, WB, IP, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:The exact immunogen used to generate this antibody is proprietary information.\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nab316974 is the carrier-free version of\u003cbr\u003e\nab316973\u003cbr\u003e\nPatented technology\u003cbr\u003e\nOur RabMAb\u003cbr\u003e\ntechnology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to\u003cbr\u003e\nRabMAb® patents\u003cbr\u003e\nWhat are the advantages of a recombinant monoclonal antibody?\u003cbr\u003e\nThis product is a recombinant monoclonal antibody, which offers several advantages including:\u003cbr\u003e\n- High batch-to-batch consistency and reproducibility\u003cbr\u003e\n- Improved sensitivity and specificity\u003cbr\u003e\n- Long-term security of supply\u003cbr\u003e\n- Animal-free batch production\u003cbr\u003e\nFor more information, read more on\u003cbr\u003e\nrecombinant antibodies\u003cbr\u003e\nConjugation ready\u003cbr\u003e\nOur carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.\u003cbr\u003e\nUse our\u003cbr\u003e\nconjugation kits\u003cbr\u003e\nfor antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.\u003cbr\u003e\nCompatibility\u003cbr\u003e\nThis product is compatible with the Maxpar\u003cbr\u003e\nAntibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar\u003cbr\u003e\nis a trademark of Fluidigm Canada Inc.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nPseudomonas Outer Membrane Porin F (OprF) is a protein in Pseudomonas aeruginosa with a molecular mass of approximately 38 kDa. It forms channels across the bacterial outer membrane and allows small hydrophilic molecules to pass functioning as a non-specific diffusion channel. OprF is essential for maintaining the structural integrity of the outer membrane and it is majorly expressed in the outer membrane of Pseudomonas species.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe Pseudomonas Outer Membrane Porin F plays an important role in nutrient uptake and waste removal. As a part of the outer membrane complex OprF works closely with other porins facilitating the transport of ions and small molecules. It contributes to the permeability of the bacterial membrane which is critical for the bacteria's adaptability and survival in diverse environments.\u003cbr\u003e\nPathways\u003cbr\u003e\nOprF is significant in the general porin-mediated transport pathways that facilitate the exchange of essential nutrients and ions. OprF interacts with other porin proteins forming part of a porous barrier that aligns with the bacteria's need for environmental adaptation. Its role is critical in the context of biofilm formation pathways and antibiotic resistance mechanisms often partnering with OprD porin in these processes.\u003cbr\u003e\nOprF is linked with chronic infections particularly in cystic fibrosis patients where Pseudomonas aeruginosa displays increased pathogenicity. OprF interacts with proteins like AlgC promoting biofilm formation that contributes to the bacterium's resistance to treatment. Its involvement in multidrug resistance also aligns with its role in chronic lung infections complicating the treatment strategies for affected individuals.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46860434505897,"sku":"ab316974","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab316974","provider":"Iright","version":"1.0","type":"link"}