{"product_id":"abcam-ab43054","title":"Abcam, ab43054, Recombinant Treponema pallidum p41 protein","description":"\u003cp\u003eSize: 200µg\u003cbr\u003e\nRecombinant Treponema pallidum p41 protein is a Fragment protein, expressed in Escherichia coli, with \u0026gt;90%, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;90% SDS-PAGE,\u003cbr\u003e\nExpression system:Escherichia coli,\u003cbr\u003e\nTags:Tag free,\u003cbr\u003e\nApplications:WB, ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nStorage buffer:pH: 8Constituents: 48% Urea, 0.158% Tris HCl, 0.0292% EDTA, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nTreponema pallidum p41 also known as Tp041 and TpN41 is a flagellin protein with a molecular mass of approximately 41 kDa. It is expressed in the flagella of Treponema pallidum which is the bacterium responsible for syphilis. The p41 protein is integral to the structural and mechanical functions of the bacterial flagellum facilitating motility and enabling the bacterium to penetrate host tissues.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nThe Treponema pallidum p41 protein plays a role in the bacterium's ability to infect host organisms. It constitutes an important part of the endoflagellar complex which allows the bacterium's distinctive spiral motion. This motion is key to invasion and colonization of host tissues as it helps the bacterium to bypass the immune defenses and reach target tissues.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe mechanical function of Treponema pallidum p41 is linked to motility pathways in bacteria. It is involved in the chemotaxis pathway which regulates movement in response to environmental stimuli. Other proteins connected to this pathway include different flagellin proteins and motor proteins that work together to maintain the bacterium's motility. These pathways are important for the infectious cycle of Treponema pallidum and its ability to navigate through host environments.\u003cbr\u003e\nTreponema pallidum p41 is closely associated with syphilis a systemic infection that impacts multiple organ systems. The ability of p41 to contribute to bacterial motility and tissue penetration makes it an important factor in the pathogenesis of the disease. Syphilis involves interactions with several host proteins but while p41 facilitates the infection process its direct interactions with host proteins during disease progression are not entirely clear indicating areas for further study in understanding syphilis pathology.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844006170793,"sku":"ab43054","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab43054","provider":"Iright","version":"1.0","type":"link"}