{"product_id":"abcam-ab49055","title":"Abcam, ab49055, Recombinant HIV1 p24 protein","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nRecombinant HIV1 p24 protein is a HIV-1 M:B_HXB2R Full Length protein, expressed in Escherichia coli, with \u0026gt;90%, suitable for ELISA, WB.\u003cbr\u003e\nKey facts\u003cbr\u003e\nPurity:\u0026gt;90% SDS-PAGE,\u003cbr\u003e\nExpression system:Escherichia coli,\u003cbr\u003e\nTags:GST tag N-Terminus,\u003cbr\u003e\nApplications:ELISA, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nBiologically active:No,\u003cbr\u003e\nAccession:P04585,\u003cbr\u003e\nAnimal free:No,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nSpecies:HIV-1 M:B_HXB2R,\u003cbr\u003e\nStorage buffer:pH: 7.2 - 7.6Constituents: 50% Glycerol (glycerin, glycerine), 9% Urea, 0.395% Tris HCl\u003c\/p\u003e\n\n\u003cp\u003eProduct details:\u003cbr\u003e\nStrongly reacts with human HIV positive serum.\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nShipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nHIV1 p24 also known as HIV p24 protein is a core protein of the Human Immunodeficiency Virus type 1 (HIV-1). The p24 protein has a molecular weight of about 24 kDa. HIV1 p24 comprises part of the viral capsid which encases the viral RNA genome. This protein is prominently expressed during the early stages of HIV infection. The presence of HIV1 p24 is commonly detected through various laboratory techniques including the use of p24 ELISA kits.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nHIV1 p24 plays an important role in the viral life cycle. It assists in the formation and stability of the viral capsid which is critical for maintaining the integrity of the viral core. HIV p24 is not a lone actor; it is part of the structural framework and interacts with other viral proteins to facilitate the viral assembly and maturation processes. The detection of HIV1 p24 is a marker for viral replication and infection stage.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe function of HIV1 p24 aligns significantly within the HIV replication pathway and the host’s immune response pathway. HIV p24 is intrinsically tied to processes of viral assembly alongside proteins like Gag and Pol coordinating to ensure successful viral replication. Furthermore the immune system recognizes the HIV1 p24 protein thereby integrating it into the host immune response which is important in disease progression and for diagnostic purposes like in the HIV ELISA assay.\u003cbr\u003e\nHIV1 p24 is integrally connected to HIV\/AIDS a disorder that profoundly affects the immune system. The presence of HIV p24 in the bloodstream is an early marker of infection and is frequently monitored to track the disease's progression. Alterations in the levels of p24 protein relate to the efficiency of therapeutic interventions. The study of HIV1 p24 also brings focus on its interaction with the CD4 receptor which is pivotal in the viral entry process further linking various stages of the HIV infection cycle to potential therapeutic targets.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46844018884777,"sku":"ab49055","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab49055","provider":"Iright","version":"1.0","type":"link"}