{"product_id":"abcam-ab70517","title":"Abcam, ab70517, Anti-C17orf57 antibody","description":"\u003cp\u003eSize: 50µg\u003cbr\u003e\nMouse Polyclonal C17orf57 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human EFCAB13.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Mouse,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:Yes,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Full Length Protein corresponding to Human EFCAB13.Q8IY85\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Protein G, Storage buffer-pH: 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nC17orf57 also known as GCP2 or GC-rich promoter binding protein 2 is a 17 kDa protein. It has a role in transcriptional regulation processes. This protein is ubiquitously expressed with higher levels in tissues such as the brain and skeletal muscle. It connects to RNA processing and possibly interacts with various components of the transcription machinery.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nC17orf57 contributes to complex processes involved in the regulation of gene expression. It interacts with some components of RNA polymerase II. This interaction suggests that C17orf57 might assist in modulating the synthesis of RNA transcripts a critical step in the flow of genetic information from DNA to protein. This protein may also play a part in nuclear processes related to mRNA stability and localization.\u003cbr\u003e\nPathways\u003cbr\u003e\nC17orf57 plays a significant role in transcription regulation and RNA processing pathways. It works alongside components in the DNA-dependent transcription pathway where interactions with RNA polymerase II are relevant. Additionally C17orf57's presence in an mRNA processing pathway suggests its involvement with proteins like GRWD1 which are associated with gene expression and regulatory events.\u003cbr\u003e\nC17orf57 has some association with cancer and neurodegenerative diseases. Studies show that its dysregulation may impact cellular processes leading to abnormal cell proliferation and possibly contributing to oncogenesis. C17orf57's interactions with proteins like CTCF may influence chromatin architecture which can impact regulatory pathways involved in these diseases. Alterations in its expression or function might also influence conditions affecting nervous system health.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46852263542953,"sku":"ab70517","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab70517","provider":"Iright","version":"1.0","type":"link"}