{"product_id":"abcam-ab77640","title":"Abcam, ab77640, Anti-LYPLAL1 antibody","description":"\u003cp\u003eSize: 200µL\u003cbr\u003e\nGoat Polyclonal LYPLAL1 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human LYPLAL1 aa 50-100.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Goat,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Human,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human LYPLAL1 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.Q5VWZ2\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab77640 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide., Storage buffer-pH: 7.3Preservative: 0.02% Sodium azideConstituents: Tris buffered saline, 0.5% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle, Store in the dark\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nLYPLAL1 also known as Lysophospholipase-like 1 is a protein involved in metabolic processes and has an approximate molecular mass of 31 kDa. This protein is expressed in various tissues with substantial levels found in adipose tissue and the liver. LYPLAL1 shows similarity to lysophospholipase enzymes but lacks the capacity to carry out specific functions typical of those enzymes. Instead LYPLAL1 contributes mechanically by modifying certain lipid molecules impacting lipid metabolism.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nLysophospholipase-like 1 influences fat storage and energy homeostasis within cells. It does not function alone but rather interacts potentially with other enzymes to regulate these processes. While LYPLAL1 itself is not part of a large complex it operates in an environment with various lipid-related enzymes that jointly maintain lipid balance in the body. Its activity can affect the breakdown of triglycerides and might have roles in metabolic regulation and efficiency.\u003cbr\u003e\nPathways\u003cbr\u003e\nLYPLAL1 integrates into lipid metabolic pathways notably lipid biosynthesis and lipid degradation. These pathways are central in balancing energy supply through the manipulation and storage of lipid molecules. Through these metabolic pathways LYPLAL1 may have connections with proteins such as hormone-sensitive lipase (HSL) which plays a significant role in lipid mobilization and perilipin which modulates lipid droplet storage. The regulation and interaction with these proteins affirm LYPLAL1's place in lipid metabolism.\u003cbr\u003e\nVariations in LYPLAL1 activity or expression have links with obesity and type 2 diabetes. The gene coding for LYPLAL1 has associations with variations impacting body mass index (BMI) and fat distribution which are critical factors in these metabolic disorders. Connections with other proteins like adiponectin which plays an important role in glucose regulation and fatty acid oxidation strengthen LYPLAL1’s involvement in these diseases. Understanding the relationship of LYPLAL1 to these conditions offers new insights into metabolic health management strategies.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854437765289,"sku":"ab77640","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab77640","provider":"Iright","version":"1.0","type":"link"}