{"product_id":"abcam-ab92350","title":"Abcam, ab92350, Anti-SCGB3A1 antibody","description":"\u003cp\u003eSize: 100µg\u003cbr\u003e\nGoat Polyclonal SCGB3A1 antibody. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human SCGB3A1 aa 50-100.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Goat,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nApplications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Synthetic Peptide within Human SCGB3A1 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.Q96QR1\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab92350 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide., Storage buffer-pH: 7.3Preservative: 0.02% Sodium azideConstituents: Tris buffered saline, 0.5% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nSCGB3A1 also known as Secretoglobin Family 3A Member 1 or Uteroglobin-Related Protein 1 is a small secretory protein with a molecular mass of approximately 10 kDa. It is mainly expressed in non-ciliated epithelial cells of the respiratory tract and also found in the prostate uterus and mammary gland tissues. The protein belongs to the secretoglobin family which is a group of small cysteine-rich secretory proteins known for their involvement in complex biological processes.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nSCGB3A1 has important roles in modulating immune response and maintaining epithelial integrity. It acts as a secreted cytokine with some anti-inflammatory properties influencing the immune cell activity and reducing inflammation. Although SCGB3A1 does not form a known complex with other proteins its function in tissue regulation indicates a significant impact on the local immune environment making it a point of interest in respiratory and reproductive health.\u003cbr\u003e\nPathways\u003cbr\u003e\nThe function of SCGB3A1 reflects its involvement in the immune signaling pathway particularly in response to inflammatory cytokines. The protein is part of a network interacting with various immune regulatory pathways including the interleukin signaling pathway. SCGB3A1 achieves this through interactions with proteins such as IL-10 which plays an important role in balancing pro-inflammatory and anti-inflammatory responses.\u003cbr\u003e\nSCGB3A1 has associations with conditions such as asthma and chronic obstructive pulmonary disease (COPD). Its anti-inflammatory functions may impact the severity and progression of these respiratory illnesses. Research links SCGB3A1 to IL-13 in the context of asthma highlighting its part in modulating the immune response within the lung tissue. This connection makes SCGB3A1 a potential target for therapeutic exploration in respiratory diseases.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46850117730473,"sku":"ab92350","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab92350","provider":"Iright","version":"1.0","type":"link"}