{"product_id":"abcam-ab97644","title":"Abcam, ab97644, Anti-C9orf78 antibody","description":"\u003cp\u003eSize: 50µL\u003cbr\u003e\nRabbit Polyclonal C9orf78 antibody. Suitable for WB, IHC-P, ICC\/IF and reacts with Mouse, Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C9orf78 aa 1-250.\u003cbr\u003e\nKey facts\u003cbr\u003e\nHost species:Rabbit,\u003cbr\u003e\nClonality:Polyclonal,\u003cbr\u003e\nIsotype:IgG,\u003cbr\u003e\nCarrier free:No,\u003cbr\u003e\nReacts with:Mouse, Rat, Human,\u003cbr\u003e\nApplications:WB, IHC-P, ICC\/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,\u003cbr\u003e\nImmunogen:Recombinant Fragment Protein within Human C9orf78 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.Q9NZ63\u003c\/p\u003e\n\n\u003cp\u003eProperties and Storage Information:\u003cbr\u003e\nForm-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7Preservative: 0.01% Thimerosal (merthiolate)Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze \/ thaw cycle\u003c\/p\u003e\n\n\u003cp\u003eSupplementary Information:\u003cbr\u003e\nThis supplementary information is collated from multiple sources and compiled automatically.\u003cbr\u003e\nC9orf78 also known as chromosome 9 open reading frame 78 is a protein with a molecular mass of approximately 24 kDa. It is expressed in various tissues but shows higher levels in the lung and reproductive organs. On a mechanical level C9orf78 is involved in intracellular processes where it interacts with other cellular components indicating its role in cellular signaling and regulation.\u003cbr\u003e\nBiological function summary\u003cbr\u003e\nC9orf78 plays a role in cellular homeostasis and regulation of metabolic processes. It acts as part of a complex that modulates cellular responses to stress and can influence gene expression. The protein's involvement in these cellular processes suggests that it serves as a mediator between cellular signaling pathways and the physical expression of cellular responses.\u003cbr\u003e\nPathways\u003cbr\u003e\nC9orf78 contributes significantly to the AMPK signaling pathway and interacts with various proteins including LKB1. This association positions it as an important factor in energy metabolism helping the cell respond to energy depletion. Its role in the cellular energy balance connects it closely to upstream and downstream signals that control cellular growth and metabolism making it important for maintaining cellular function.\u003cbr\u003e\nC9orf78 is associated with complex conditions like metabolic syndrome and cancer. It links to disease progression possibly through its relationship with AMPK as dysregulation in this pathway can lead to metabolic imbalance and growth irregularities. Additionally its interaction with proteins like LKB1 known for its tumor suppressive functions further emphasizes the importance of C9orf78 in maintaining normal cellular operations and its potential impact when malfunctioning.\u003c\/p\u003e","brand":"Abcam","offers":[{"title":"Default Title","offer_id":46854222545065,"sku":"ab97644","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/abcam-ab97644","provider":"Iright","version":"1.0","type":"link"}