{"product_id":"biolegend-102706","title":"Biolegend, 102706, FITC anti-mouse CD38 Antibody, 500μg","description":"\u003cp\u003eCD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse bone marrow pre-B cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nProduct Citations: He Y, et al. 2023. Nat Commun. 14:691. PubMed Luo Z, et al. 2020. Front Immunol. 0.883333333. PubMed Matsumura T et al. 2019. Cell Rep. 27(2):561-571 . PubMed Duan L, et al. 2021. Immunity. 54:2256. PubMed Chen M, et al. 2016. J Immunol . 194: 2607-15. PubMed Onodera T, et al. 2016. J Immunol. 196: 4172 - 4184. PubMed Iizasa E, et al. 2021. Nat Commun. 12:2299. PubMed Schoeler K, et al. 2019. FEBS J. 10.1111\/febs.14934. PubMed Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed Ganesan R, et al. 2020. FASEB J. 34:15888. PubMed Chiu Y, et al. 2014. J Immunol. 193:2207. PubMed Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed Ma X, et al. 2020. Immunity. 53:1315. PubMed Andriessen EMMA, et al. 2021. EMBO Mol Med. 13:e11754. PubMed Chuang YT, et al. 2019. J Allergy Clin Immunol. 143:565. PubMed Jablonski K, et al. 2015. PLoS One. 10: 0145342. PubMed Ryg-Cornejo V, et al. 2016. Cell Rep. 14:68-81. PubMed Adachi Y, et al. 2015. J Exp Med. 212: 1709-1723. PubMed Rodrigues KA, et al. 2021. Sci Adv. 7:eabj6538. PubMed\u003cbr\u003e\nRRID: AB_312926 (BioLegend Cat. No. 102705)\u003cbr\u003e\nStructure: ADP-ribosyl hydrolase, 42 kD\u003cbr\u003e\nDistribution: B cells, NK cells, T cell subset, brain, muscle, kidney\u003cbr\u003e\nFunction: Regulation of cellular activation\/proliferation, adhesion, metabolism of cADPR and NAADP\u003cbr\u003e\nLigand\/Receptor: CD31, hyaluronic acid\u003cbr\u003e\nAntigen References: 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Shubinsky G, et al. 1997. Immunity 7:315. 3. Cesano A, et al. 1998. J. Immunol. 160:1106. 4. Cockayne DA, et al. 1998. Blood 92:1324.\u003cbr\u003e\nGene ID: 12494\u003cbr\u003e\nUniProt: View information about CD38 on UniProt.org\u003cbr\u003e\nClone: 90\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T10\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862497710249,"sku":"102706","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-102706","provider":"Iright","version":"1.0","type":"link"}