{"product_id":"biolegend-107902","title":"Biolegend, 107902, Purified anti-mouse Podocalyxin Antibody, 100μg","description":"\u003cp\u003ePodocalyxin is sialomucin, most closely related to CD34 and endoglycan, expressed by kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons. It regulates both cell adhesion and cell morphology and plays an essential role in the formation of podocyte foot processes.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: OSM-dependent endothelial-like cell line, LO\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested IHC-F - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. For immunohistochemistry on frozen tissue sections, a concentration range of 2.0 - 5.0 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Onitsuka, I., et al., 2010. Gastroenterology, 138:1525-1535. Doyonnas, R., et al., 2005. Blood, 105:4170-4178. Minegishi, N., et al., 2003. Blood, 102:896-905. Minehata, K., et al., 2002. Blood, 99:2360-2368. Doyonnas, R., et al., 2001. J. Exp. Med., 194:13-28. Hara, T., et al., 1999. Immunity, 11:567-578.\u003cbr\u003e\nRRID: AB_2904281 (BioLegend Cat. No. 107902)\u003cbr\u003e\nStructure: Single-pass type I membrane protein, sialoglycoprotein\u003cbr\u003e\nDistribution: Apical cell membrane, membrane raft\u003cbr\u003e\nFunction: Cell adhesion, cell migration\u003cbr\u003e\nInteraction: Forms a complex with EZR and SLC9A3R2.\u003cbr\u003e\nBiology Area: Apoptosis\/Tumor Suppressors\/Cell Death, Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology\u003cbr\u003e\nAntigen References: Refaeli I, et al. 2020. Scientific Reports 10:9419 Economou C, et al. 2004. J Cell Sci (2004) 117 (15): 3281–94. Cait J, et al. 2019. Proc Natl Acad Sci. 116 (10) 4518-4527 Doyonnas R, et al. 2005. Blood. 105(11):4170-8 Zhang H, et al. 2014. Stem Cells. 32(1):191-203\u003cbr\u003e\nGene ID: 27205\u003cbr\u003e\nUniProt: View information about Podocalyxin on UniProt.org\u003cbr\u003e\nClone: 10B9\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Podocalyxin\u003cbr\u003e\nIsotype: Rat IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860778307753,"sku":"107902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-107902","provider":"Iright","version":"1.0","type":"link"}