{"product_id":"biolegend-110905","title":"Biolegend, 110905, APC anti-mouse CD103 Antibody, 25μg","description":"\u003cp\u003eCD103 is the alpha E integrin, which forms a heterodimer with integrin beta 7. The heterodimer complex binds to E-cadherin. It is expressed in on T cells, notably in subpopulations in the lamina propria, on regulatory T cells, or resident memory T cells, and a subset of dendritic cells in gut mucosa. CD103 is thought to be involved with homing to intestinal epithelial sites and has been associated with high levels of TGF-beta presence.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Recombinant mouse integrin alphaE\/beta7\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Clone W19396D can partially block binding of clone 2E7 on target cells.\u003cbr\u003e\nRRID: AB_2927988 (BioLegend Cat. No. 110905) AB_2927988 (BioLegend Cat. No. 110906)\u003cbr\u003e\nStructure: 125 - 150 kD transmembrane glycoprotein, integrin\u003cbr\u003e\nDistribution: Lamina propria T cells, regulatory T cells, resident memory T cells, subset of dendritic cells\u003cbr\u003e\nFunction: Adhesion, localization and activation of intestinal lymphocytes, lymphocyte homing\u003cbr\u003e\nInteraction: Integrin β7\u003cbr\u003e\nLigand\/Receptor: E-Cadherin\u003cbr\u003e\nCell Type: Dendritic cells, Lymphocytes, T cells, Tregs\u003cbr\u003e\nBiology Area: Cell Adhesion, Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Parker CM, et al. 1992. Proc Natl Acad Sci U S A. 89:1924-8. Kruschwitz M, et al. 1991. J Clin Pathol. 44:636-45. Schon MP, et al. 1999. J. Immunol. 162:6641-9. Shaw SK, et al. 1994. J Biol Chem. 269:6016-25.\u003cbr\u003e\nGene ID: 3682\u003cbr\u003e\nUniProt: View information about CD103 on UniProt.org\u003cbr\u003e\nClone: W19396D\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD103, ITAGE, integrin alpha E\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866415878313,"sku":"110905","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-110905","provider":"Iright","version":"1.0","type":"link"}