{"product_id":"biolegend-115406","title":"Biolegend, 115406, PE\/Cyanine7 anti-mouse Integrin αVβ8 Antibody, 100μg","description":"\u003cp\u003eIntegrins are heterodimeric transmembrane receptors that mediate cell-cell and cell-extracellular matrix adhesion. Integrin αVβ8 is also involved in TGF-β activation, which contributes to regulatory T cell (Treg) activities.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse αVβ8 integrin-transfected cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Clone S20011E does not affect the binding of clone S20011B on target cells. Clone S20011E does not react with mouse integrin αVβ6.\u003cbr\u003e\nRRID: AB_3662178 (BioLegend Cat. No. 115405) AB_3662178 (BioLegend Cat. No. 115406)\u003cbr\u003e\nStructure: Integrins\u003cbr\u003e\nDistribution: Epithelial cells\u003cbr\u003e\nFunction: Cell adhesion, TGF-β activation\u003cbr\u003e\nCell Type: Epithelial cells, Tregs\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology, Immuno-Oncology, Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules\u003cbr\u003e\nAntigen References: Moyle M, et al. 1991. J Biol Chem. 266:19650-8\u003cbr\u003e\nGene ID: 16410320910\u003cbr\u003e\nUniProt: View information about Integrin alphaVbeta8 on UniProt.org\u003cbr\u003e\nClone: S20011E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Integrin alpha V beta 8\u003cbr\u003e\nIsotype: Rat IgG2b, λ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866264883369,"sku":"115406","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-115406","provider":"Iright","version":"1.0","type":"link"}