{"product_id":"biolegend-115501","title":"Biolegend, 115501, Purified anti-mouse CD19 Antibody, 50μg","description":"\u003cp\u003eCD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.\u003cbr\u003e\n50μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CD19-expressing K562 human erythroleukemia cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested CyTOF® - Verified IHC-F - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunofluorescence7.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Shoham T, et al. 2003. J. Immunol. 171:4062. (FC) Goodyear CS, et al. 2004. J. Immunol. 172:2870. (FC) Kamimura D, et al. 2006. J. Immunol. 177:306. (FC) Andoniou CE, et al. 2005. Nat. Immunol. 6:1011. (FC) Lawson BR, et al. 2007. J. Immunol. 178:5366. (FC) Phan TG, et al. 2007. Nat. Immunol. 8:992. (FC) Hayashida K, et al. 2008. J. Biol. Chem. 283:19895. (IF) PubMed Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed Stadnisky MD, et al. 2011. Blood. 117:5133. (FC) PubMed Perlot T, et al. 2012. J. Immunol. 188:1201. (FC) PubMed Olive V, et al. 2013. Elife. 2:822. PubMed Miyai T, et al. 2014. PNAS. 111:11780. PubMed\u003cbr\u003e\nProduct Citations: Hu J, et al. 2019. Am J Transl Res. 3.043055556. PubMed Yuan X, et al. 2023. J Periodontol. 94:277. PubMed Tersteegen A, et al. 2021. Infect Immun. 89:. PubMed Liu CJ, et al. 2020. Neuro Oncol. 22:1276. PubMed Doll JR, et al. 2020. PLoS Pathog. 16:e1008296. PubMed Li H, et al. 2022. Cancer Cell. 40:36. PubMed Valet C, et al. 2022. J Clin Invest. 132: . PubMed Moore AR, et al. 2022. Cell Rep. 41:111651. PubMed Potempa M, et al. 2022. J Immunol. 208:1742. PubMed Hailemichael Y, et al. 2022. Cancer Cell. 40:509. PubMed Mazor R, et al. 2018. Proc Natl Acad Sci U S A. 115:E733. PubMed Fernandes V, et al. 2020. PLoS Pathog. 16:e1008464. PubMed Wan Mohd Zawawi WFA, et al. 2021. Sci Rep. 11:10278. PubMed Boal-Carvalho I, et al. 2020. EMBO Rep. 21:e50421. PubMed Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed Field CS, et al. 2018. Oncoimmunology. 7:e1376154. PubMed Carpenter SM, et al. 2017. PLoS Pathog. 13:e1006704. PubMed Thulasingam S, et al. 2019. Int J Mol Sci. 20. PubMed Schafflick D, et al. 2020. Nat Commun. 247:11. PubMed Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed Joseph R, et al. 2021. Br J Cancer. 125:176. PubMed Taylor NA, et al. 2017. J Clin Invest. 127:3472. PubMed Khan KA, et al. 2020. NPJ Breast Cancer. 6:29. PubMed Hilligan KL, et al. 2020. Nat Commun. 11:5637. PubMed Suzuki Y, et al. 2021. FEBS Open Bio. 11:2619. PubMed Yan J, et al. 2020. Cancer Immunol Res. 8:356. PubMed Chen L, et al. 2020. Front Immunol. 11:584458. PubMed Manni M, et al. 2018. Nat Immunol. 1.074305556. PubMed He LD, et al. 2021. EMBO Rep. 22:e52196. PubMed Ma W, et al. 2017. Sci Rep. . 10.1038\/s41598-017-15661-6. PubMed Lim PJ, et al. 2019. Nat Metab. 0.402083333. PubMed McFarlane AJ, et al. 2017. J Allergy Clin Immunol. 140:1068. PubMed Borges TJ, et al. 2018. Nat Commun. 9:3482. PubMed Hoves S, et al. 2018. J Exp Med. 215:859. PubMed Godoy-Calderón MJ, et al. 2018. Oncotarget. 8:11370. PubMed Nascimento DC, et al. 2017. Nat Commun. 8:14919. PubMed Shin J, et al. 2018. Diabetes. 67:1068. PubMed Majer O, et al. 2019. Nature. 575:366. PubMed You X, et al. 2022. Front Genet. 12:790990. PubMed Zelazowska MA, et al. 2020. Life Sci Alliance. :3. PubMed Rozanski C, et al. 2015. J Immunol. 194:4717. PubMed Oyarce K, et al. 2018. Front Immunol. 9:112. PubMed Chen HW, et al. 2021. Biomedicines. 9:. PubMed Gubin MM, et al. 2018. Cell. 175:1014. PubMed Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed Rigo MM, et al. 2020. FEBS J. :. PubMed Goh W, et al. 2020. Cell Rep. 33:108285. PubMed Seo SU, et al. 2021. Front Immunol. 12:697162. PubMed Yang J, et al. 2019. Front Immunol. 2.492361111. PubMed Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed Majri SS, et al. 2018. J Immunol. 200:110. PubMed Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed Brownlie D, et al. 2021. J Immunother Cancer. 9:. PubMed Cui X, et al. 2017. J Immunol. 199:4066. PubMed Penninger T 2012. J Immunol. 188:1201. PubMed Korin B, et al. 2020. Sleep. :43. PubMed Zhu J et al. 2017. Cell stem cell. 20(3):374-384 . PubMed Hayashida K, et al. 2008. J Biol Chem. 283:19895. PubMed Stevens MY, et al. 2020. J Neuroinflammation. 0.899305556. PubMed Englezou PC, et al. 2018. Mol Ther Nucleic Acids. 12:118. PubMed Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed Atif SM, et al. 2019. JCI Insight. 4:e125494. PubMed Leist SR, et al. 2019. PLoS One. 14:e0220126. PubMed Khameneh HJ, et al. 2017. J Immunol. 198:196. PubMed Stadnisky M, et al. 2011. Blood. 117:5133. PubMed Chen YQ, et al. 2019. J Immunother Cancer. 0.415277778. PubMed Kästele V, et al. 2021. Mucosal Immunol. 14:717. PubMed Hwang JY, et al. 2020. Front Immunol. 11:570661. PubMed Sutiwisesak R, et al. 2020. PLoS Pathog. 16:e1009000. PubMed\u003cbr\u003e\nRRID: AB_313636 (BioLegend Cat. No. 115501) AB_313637 (BioLegend Cat. No. 115502)\u003cbr\u003e\nStructure: Ig superfamily, associates with CD21 and CD81, 95 kD\u003cbr\u003e\nDistribution: Pro-B cells to mature B cells (during development), follicular dendritic cells\u003cbr\u003e\nFunction: Modulates B cell activation and differentiation\u003cbr\u003e\nLigand\/Receptor: CD21, CD81, Leu-13\u003cbr\u003e\nCell Type: B cells, Dendritic cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341. 2. Krop I, et al. 1996. Eur. J. Immunol. 26:238. 3. Krop I, et al. 1996. J. Immunol. 157:48. 4. Tedder TF, et al. 1994. Immunol. Today 15:437.\u003cbr\u003e\nGene ID: 12478\u003cbr\u003e\nUniProt: View information about CD19 on UniProt.org\u003cbr\u003e\nClone: 6D5\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: B4\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862477131945,"sku":"115501","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-115501","provider":"Iright","version":"1.0","type":"link"}