{"product_id":"biolegend-127412","title":"Biolegend, 127412, PE\/Cyanine7 anti-mouse Podoplanin Antibody, 100μg","description":"\u003cp\u003eThe mucin-type glycoprotein podoplanin is thought to be involved in the development of the lymphatic vascular system. Podoplanin is named after its expression in the kidney glomerular epithelial cells (podocytes). It has a potential role in tumor progression.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Syrian Hamster\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunohistochemistry6, and spatial biology (IBEX)8,9.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Farr A, et al. 1992. J. Histochem. Cytochem. 40:651. Farr AG, et al. 1992. J. Exp. Med. 176:1477. Bekiaris V, et al. 2008. J. Immunol. 180:6768. Algars A, et al. 2011. Blood 117:4387. PubMed Reis VO, et al. 2012. Immunobiology. 217:831. PubMed Kaji C, et al. 2012. Acta. Histochem. Cytochem. 45:227. (IHC) Kretschmer S, et al. 2013. PLoS One. 8:e52201. PubMed. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed\u003cbr\u003e\nProduct Citations: Brulois K, et al. 2020. Nat Commun. 3.095833333. PubMed Korsunsky I, et al. 2022. Med. 3:481. PubMed Lütge M, et al. 2023. Nat Immunol. . PubMed Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed Alexandre YO, et al. 2022. STAR Protoc. 3:101923. PubMed Li X, et al. 2022. Nat Commun. 13:2794. PubMed McCarthy N, et al. 2020. Cell Stem Cell. 391:26. PubMed Quaife-Ryan GA, et al. 2020. Development. 147: . PubMed Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed Armaka M, et al. 2022. Genome Med. 14:78. PubMed Rodriguez AB, et al. 2021. Cell Reports. 36(3):109422. PubMed Jackson-Jones LH, et al. 2020. Immunity. 52:700. PubMed Thiriot A et al. 2017. BMC biology. 15(1):45 . PubMed Ferreirinha P, et al. 2022. Development. 149: . PubMed Auvinen K, et al. 2019. Sci Rep. 9:15698. PubMed Stifter SA, et al. 2019. Cell Rep. 29:3539. PubMed Huetter J, et al. 2020. Cancer Immunol Res. 0.954861111. PubMed Alexandre YO, et al. 2020. Cell Reports. 33(13):108567. PubMed Hong SP, et al. 2020. Nat Commun. 3.306944444. PubMed Woods S, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 308:912. PubMed Dahlgren MW et al. 2019. Immunity. 50(3):707-722 . PubMed Xu C, et al. 2018. Nat Commun. 9:2449. PubMed Rodriguez AB, et al. 2022. Front Immunol. 13:1009306. PubMed Mello AM, et al. 2022. Oncogenesis. 11:56. PubMed Urbanska AM, et al. 2020. Cancer Biother Radiopharm. 35:459. PubMed Sitnik K, et al. 2012. J Immunol. 188:4801. PubMed Benezech C, Caamano J 2013. J Vis Exp. 82: 50952. PubMed Lai NY, et al. 2020. Cell. 180:33:00. PubMed Hsu HP, et al. 2021. J Biol Chem. 296:100419. PubMed Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed Thomson CA, et al. 2018. J Immunol. 201:215. PubMed Barry DM, et al. 2019. Nat Commun. 4.378472222. PubMed Quaife-Ryan GA, et al. 2020. Development. . PubMed\u003cbr\u003e\nRRID: AB_10613294 (BioLegend Cat. No. 127411) AB_10613648 (BioLegend Cat. No. 127412)\u003cbr\u003e\nStructure: 43 Kd glycosylated type-1 transmembrane protein. Mucin-type protein.\u003cbr\u003e\nDistribution: Expressed on epithelial and mesothelial cells.\u003cbr\u003e\nCell Type: Epithelial cells\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nAntigen References: 1. Farr A, et al. 1992. J. Histochem. Cytochem. 40:651. 2. Schacht V, et al. 2005. Am. J. Pathol. 166:913.\u003cbr\u003e\nGene ID: 14726\u003cbr\u003e\nUniProt: View information about Podoplanin on UniProt.org\u003cbr\u003e\nClone: 8.1.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T1a, gp38, stromal cell marker\u003cbr\u003e\nIsotype: Syrian Hamster IgG\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862490960041,"sku":"127412","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-127412","provider":"Iright","version":"1.0","type":"link"}