{"product_id":"biolegend-127908","title":"Biolegend, 127908, PE anti-mouse TCR Vβ2 Antibody, 100μg","description":"\u003cp\u003eThe B20.6 antibody recognizes V beta 2 TCR of all strains tested. V beta 2 bearing T lymphocytes are clonally eliminated in MHC class II I-E expressing mice neonatally infected with MMTV virus through milk feeding.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Soluble TCR from mouse CTL clone CW3\/1.1\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Necker A, et al. 1991. Eur J. Immunol. 21:3035 Hodes RJ, et al. 1993. J Immunol 150:1422\u003cbr\u003e\nProduct Citations: Lutes LK, et al. 2021. eLife. 10:00. PubMed Zhang F, et al. 2019. Nat Commun. 10:3974. PubMed Nelson CE et al. 2019. Cell Rep. 28(12):3092-3104 . PubMed\u003cbr\u003e\nRRID: AB_1227785 (BioLegend Cat. No. 127907) AB_1227784 (BioLegend Cat. No. 127908)\u003cbr\u003e\nStructure: TCR has a two chain structure, consisting of alpha and beta chain. It belongs to Ig superfamily.\u003cbr\u003e\nDistribution: On a subset of T cells\u003cbr\u003e\nFunction: Recognize MHC\/peptide complex on the antigen-presenting cells.\u003cbr\u003e\nInteraction: Associate with V alpha and CD3 complex to form TCR complexes expressing on cell surface.\u003cbr\u003e\nLigand\/Receptor: TCR recognizes MHC\/peptide complex\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Kubo RT, et al. 1989. J. Immunol. 142:2736 2. Necker A, et al. 1991. Eur. J. Immunol. 21:3035\u003cbr\u003e\nGene ID: 21577\u003cbr\u003e\nUniProt: View information about TCR Vbeta2 on UniProt.org\u003cbr\u003e\nClone: B20.6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor Vβ 2 [vb2]\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862549549225,"sku":"127908","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-127908","provider":"Iright","version":"1.0","type":"link"}