{"product_id":"biolegend-133103","title":"Biolegend, 133103, PE anti-mouse CD79a (Igα) Antibody, 50μg","description":"\u003cp\u003eMouse CD79a (Ig α chain) is a 47 kD type I integral membrane protein, known as mb-1 or Ig α. It forms a heterodimer with CD79b (Ig β chain). The CD79a and CD79b heterodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79a may play a role in mediating the transport of IgM to the cell surface. Clone F11-172 antibody recognizes the 47 kD membrane glycoprotein present on B lymphocytes.\u003cbr\u003e\n50μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Armenian Hamster\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Kraus M, et al. 2001. J. Exp. Med. 194:455\u003cbr\u003e\nProduct Citations: Saxena N, et al. 2018. Asian Pac J Cancer Prev. 19:81. PubMed\u003cbr\u003e\nRRID: AB_1595633 (BioLegend Cat. No. 133103)\u003cbr\u003e\nStructure: A 47 kD membrane glycoprotein which associates with CD79b to form part of B-cell receptor complex.\u003cbr\u003e\nDistribution: CD79a is expressed on B cells at various differentiation stages, from pre-B cell to plasma cells. It is expressed probably before expression of cytoplasmic µu chain.\u003cbr\u003e\nFunction: Mediating the transport of IgM to the cell surface.\u003cbr\u003e\nLigand\/Receptor: CD79a\/CD79b heterodimers are associated with surface IgM to form B cell receptor complex (BCR) to recognize specific antigen.\u003cbr\u003e\nCell Type: B cells, Plasma cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Schamel W, et al. 2000. Immunity 13:5 2. Taddie JA, et al. 1994. J. Biol. Chem. 269:13529\u003cbr\u003e\nGene ID: 12518\u003cbr\u003e\nUniProt: View information about CD79a on UniProt.org\u003cbr\u003e\nClone: F11-172\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Mb-1, Igα\u003cbr\u003e\nIsotype: Armenian Hamster IgG\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46863080128681,"sku":"133103","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-133103","provider":"Iright","version":"1.0","type":"link"}