{"product_id":"biolegend-138504","title":"Biolegend, 138504, PE anti-mouse CD24 Antibody, 200μg","description":"\u003cp\u003eCD24 is a 35-45 kD protein, also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, hematopoietic stem cells, and neurons. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.\u003cbr\u003e\n200μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse thymus\/spleen\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (FC)\u003cbr\u003e\nProduct Citations: Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed Ruan X, et al. 2023. Nat Commun. 14:3275. PubMed Varshney R, et al. 2023. iScience. 26:105750. PubMed Bommireddy R, et al. 2020. Vaccines (Basel). 8:. PubMed Perry JSA, et al. 2018. Immunity. 48:923. PubMed Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed Upadhya R, et al. 2016. MBio. 7: 00547-16. PubMed Bradley T et al. 2018. Cell reports. 25(1):107-117 . PubMed Kishi Y, et al. 2021. STAR Protocols. 2(2):100540. PubMed Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed\u003cbr\u003e\nRRID: AB_10576359 (BioLegend Cat. No. 138503) AB_10578416 (BioLegend Cat. No. 138504)\u003cbr\u003e\nStructure: GPI-linked sialoglycoprotein, 35-45 kD.\u003cbr\u003e\nDistribution: Lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, and neurons\u003cbr\u003e\nFunction: Regulate B and T cell proliferation and differentiation.\u003cbr\u003e\nLigand\/Receptor: P-selectin, CD24\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Epithelial cells, Erythrocytes, Granulocytes, Lymphocytes, Monocytes, Neurons, Thymocytes\u003cbr\u003e\nBiology Area: Cell Biology, Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Li YS, et al. 1993. J. Exp. Med. 178:951. 2. Aigner S, et al. 1995. Int. Immunol. 7:1557. 3. Hunte BE, et al. 1998. Eur. J. Immunol.. 28:3850. 4. Auerbach R, et al. 1996. Stem Cells 14:269. 5. Allman DM, et al. 1993. J. Immunol.. 151:4431.\u003cbr\u003e\nGene ID: 12484\u003cbr\u003e\nUniProt: View information about CD24 on UniProt.org\u003cbr\u003e\nClone: 30-F1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Heat Stable Antigen (HSA), HsAg, Ly-52, Nectadrin\u003cbr\u003e\nIsotype: Rat IgG2c, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862335770793,"sku":"138504","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-138504","provider":"Iright","version":"1.0","type":"link"}