{"product_id":"biolegend-138506","title":"Biolegend, 138506, APC anti-mouse CD24 Antibody, 100μg","description":"\u003cp\u003eCD24 is a 35-45 kD protein, also known as Heat Stable Antigen (HSA), Ly-52, or Nectadrin. It is a GPI-linked sialoglycoprotein expressed on lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, hematopoietic stem cells, and neurons. CD24 expression varies during T and B cell differentiation and is a useful marker for delineating various lymphocyte developmental stages. CD24 serves as an adhesion or costimulatory molecule involved in T and B lymphocyte activation and differentiation by homophilic binding or binding to CD62P.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse thymus\/spleen\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (FC)\u003cbr\u003e\nProduct Citations: Zhang AQ, et al. 2023. Nat Biomed Eng. . PubMed Xia KS, et al. 2023. Bioact Mater. 21:69. PubMed Feng H, et al. 2020. J Clin Invest. 130:6354. PubMed Zhou W, et al. 2019. Cell Syst. 0.597916667. PubMed Nguyen SL, et al. 2021. Sci Rep. 11:4217. PubMed Paiva RS, et al. 2021. Eur J Immunol. 51:1968. PubMed Wang L, et al. 2021. Cancer Immunol Res. 9:348. PubMed Jiang G, et al. 2021. Cell Death Dis. 12:979. PubMed Zhang H, et al. 2019. Mol Cell. 76:110. PubMed Lehrke MJ, et al. 2021. Elife. 10:. PubMed Lu X, et al. 2019. Cell Rep. 28:472. PubMed Shen Y, et al. 2022. Cell Death Dis. 13:749. PubMed Mead BE et al. 2018. BMC biology. 16(1):62 . PubMed Ying Z, et al. 2020. Cell Stem Cell. 26(3):403-419. PubMed Han Y, et al. 2019. J Clin Invest. 130:26. PubMed\u003cbr\u003e\nRRID: AB_2565650 (BioLegend Cat. No. 138505) AB_2565651 (BioLegend Cat. No. 138506)\u003cbr\u003e\nStructure: GPI-linked sialoglycoprotein, 35-45 kD.\u003cbr\u003e\nDistribution: Lymphocytes, granulocytes, epithelial cells, thymocytes, monocytes, erythrocytes, dendritic cells, and neurons\u003cbr\u003e\nFunction: Regulate B and T cell proliferation and differentiation.\u003cbr\u003e\nLigand\/Receptor: P-selectin, CD24\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Epithelial cells, Erythrocytes, Granulocytes, Lymphocytes, Monocytes, Neurons, Thymocytes\u003cbr\u003e\nBiology Area: Cell Biology, Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Li YS, et al. 1993. J. Exp. Med. 178:951. 2. Aigner S, et al. 1995. Int. Immunol. 7:1557. 3. Hunte BE, et al. 1998. Eur. J. Immunol.. 28:3850. 4. Auerbach R, et al. 1996. Stem Cells 14:269. 5. Allman DM, et al. 1993. J. Immunol.. 151:4431.\u003cbr\u003e\nGene ID: 12484\u003cbr\u003e\nUniProt: View information about CD24 on UniProt.org\u003cbr\u003e\nClone: 30-F1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Heat Stable Antigen (HSA), HsAg, Ly-52, Nectadrin\u003cbr\u003e\nIsotype: Rat IgG2c, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862335705257,"sku":"138506","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-138506","provider":"Iright","version":"1.0","type":"link"}