{"product_id":"biolegend-138604","title":"Biolegend, 138604, PE anti-mouse Ly-6D Antibody, 100μg","description":"\u003cp\u003eLymphocyte antigen 6D (Ly-6D), also known as thymocyte B-cell antigen (ThB), is a 16 kD GPI-linked cell surface glycoprotein. It belongs to the Ly6 gene family and contains one urokinase receptor (uPAR) \/Ly6 domain. Ly-6D is involved in cell-cell adhesion and signal transduction. Ly-6D marks the earliest stage of B cell lineage commitment from the common lymphoid progenitors (CLP). It is expressed on B cells, immature thymocytes, and plasmacytoid dendritic cells.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: BALB\/c mouse plasmacytoma MOPC-104E\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Eckhardt LA and Herzenberg LA. 1980. Immunogenetics 11:275. (FC)\u003cbr\u003e\nProduct Citations: Zhou W, et al. 2019. Cell Syst. 0.597916667. PubMed Miyazaki M et al. 2017. Immunity. 46(5):818-834 . PubMed Semba T, et al. 2020. Cancers (Basel). 12:. PubMed Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed Huang X, et al. 2021. Immunity. . PubMed\u003cbr\u003e\nRRID: AB_2281362 (BioLegend Cat. No. 138603) AB_2137349 (BioLegend Cat. No. 138604)\u003cbr\u003e\nStructure: GPI-linked cell-surface glycoprotein, molecular weight 16 kD, belongs to the Ly6 gene family, contains one urokinase receptor (uPAR) \/Ly6 domain\u003cbr\u003e\nDistribution: B cells, B cell-biased lymphoid progenitor (BLP), thymocytes, plasmacytoid dendritic cells\u003cbr\u003e\nFunction: Cell-cell adhesion and signal transduction\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Thymocytes\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology, Immunology, Signal Transduction\u003cbr\u003e\nMolecular Family: Adhesion Molecules\u003cbr\u003e\nAntigen References: 1. Inlay MA, et al. 2009. Genes Dev. 23:2376. 2. Gumley TP, et al. 1995. Immunol. Cell Biol. 73:277. 3. Mansson R, et al. 2010. Blood 115:2601. 4. Reese JT, et al. 2001. Dev. Immunol. 8:107.\u003cbr\u003e\nGene ID: 17068\u003cbr\u003e\nUniProt: View information about Ly-6D on UniProt.org\u003cbr\u003e\nClone: 49-H4\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Lymphocyte antigen 6D, Thymocyte B-cell antigen, ThB\u003cbr\u003e\nIsotype: Rat IgG2c, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862406910121,"sku":"138604","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-138604","provider":"Iright","version":"1.0","type":"link"}