{"product_id":"biolegend-140309","title":"Biolegend, 140309, PE\/Cyanine7 anti-mouse CD90.2 (Thy1.2) Antibody, 25μg","description":"\u003cp\u003eCD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2, a GPI-linked membrane molecule. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb\/c, CBA\/J, C3H\/He, C57BL\/-, DBA, NZB\/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse thymus or spleen\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.06 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunohistochemical staining1 of frozen tissue section, immunofluorescence2, and immunoprecipitation3. Does not react with Thy-1.1 (CD90.1).\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Aldrich M, et al. 2003. J. Immunol. 171:5562. (IHC) Jameson J, et al. 2004. J. Immunol. 172:3573. (IF) Okada C, et al. 1990. J. Immunol. 144:3473. (IP)\u003cbr\u003e\nProduct Citations: Aso K, et al. 2023. Nat Commun. 14:984. PubMed Giannou AD, et al. 2023. Immunity. 56:125. PubMed Karagiannis F, et al. 2020. Immunity. 52(4):620-634. PubMed Wang D, et al. 2018. Immunity. 48:659. PubMed Kobayashi T, et al. 2019. Cell. 176:982. PubMed Wu L, et al. 2021. Cell Prolif. 54:e13133. PubMed Chun E, et al. 2020. Immunity. 51(5):871-884.e6.. PubMed Pfenninger P, et al. 2022. Front Immunol. 13:777113. PubMed Miguel R, et al. 2012. J Immunol. 189:3449. PubMed He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed Brown CC, et al. 2020. Cell. 179(4):846-863.e24.. PubMed Hollmann C, et al. 2016. J Immunol. 197: 3130 - 3141. PubMed Chen J, et al. 2016. Cell Rep. S2211-1247(16)00033-4. PubMed Consalvi S, et al. 2022. EMBO Rep. 23:e54721. PubMed Kovacs SB, et al. 2021. STAR Protoc. 2:100244. PubMed Evrard M et al. 2018. Immunity. 48(2):364-379 . PubMed Kovacs SB, et al. 2020. Cell Reports. 32(4):107967. PubMed Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed\u003cbr\u003e\nRRID: AB_10645336 (BioLegend Cat. No. 140309) AB_10643586 (BioLegend Cat. No. 140310)\u003cbr\u003e\nStructure: Ig superfamily, 25-35 kD\u003cbr\u003e\nDistribution: Hematopoietic stem cells and neurons, epithelial cells, fibroblasts, neurons, all thymocytes, and peripheral T cells of Thy-1.2 bearing mice\u003cbr\u003e\nFunction: Lymphocyte costimulation, proliferation, and differentiation of hematopoietic stem cells\u003cbr\u003e\nLigand\/Receptor: CD45\u003cbr\u003e\nCell Type: Epithelial cells, Fibroblasts, Hematopoietic stem and progenitors, Neurons, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Apoptosis\/Tumor Suppressors\/Cell Death, Cell Biology, Immunology, Signal Transduction\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Borrello M, et al. 1996. Cell. Immunol.173:198. 2. Radrizzani M, et al. 1995. J. Neurosci. Res. 42:220. 3. Williams A, et al. 1982. Science 216:696.\u003cbr\u003e\nGene ID: 21838\u003cbr\u003e\nUniProt: View information about CD90.2 on UniProt.org\u003cbr\u003e\nClone: 53-2.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Thy-1.2\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862430044329,"sku":"140309","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-140309","provider":"Iright","version":"1.0","type":"link"}