{"product_id":"biolegend-142502","title":"Biolegend, 142502, Purified anti-mouse CD138 (Syndecan-1) Antibody, 500μg","description":"\u003cp\u003eCD138, a member of the syndecan protein family, is a type I integral membrane heparin sulfate proteoglycan also known as Syndecan-1. Syndecan-1 participates in cell proliferation, cell migration, and cell matrix adhesion via interaction with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-B cells, mesenchymal cells, epithelial cells, and endothelial cells.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse mammary gland epithelial cell line NMuMG\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested ICC, IHC-P, IHC-F - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen tissue3 and formalin-fixed paraffin embedded tissue4 and immunofluorescent staining2,3.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Jalkanen M, et al. 1985. J. Cell. Biol. 101:976. (FC) Miettinen H, et al. 1994. J. Cell. Sci. 107:1571. (IF) Li Q, et al. 2002. Cell 111:635. (IF, IHC) McCarthy BA, et al. 2012. BMC Cancer. 12:203. (IHC)\u003cbr\u003e\nProduct Citations: Papoutsopoulou S, et al. 2022. Am J Physiol Gastrointest Liver Physiol. 323:G306. PubMed Kobayashi A, et al. 2021. Front Immunol. 12:650856. PubMed Valet C, et al. 2022. J Clin Invest. 132: . PubMed Agrafiotis A, et al. 2023. Acta Neuropathol. 145:335. PubMed Yao W, et al. 2019. Nature. 568:410. PubMed Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed McBride KM, et al. 2019. Front Oncol. 9:517. PubMed Tran JQ, et al. 2020. Blood Adv. 4:5547. PubMed Akhmetzyanova I, et al. 2020. Leukemia. 34:245. PubMed Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed Majer O, et al. 2019. Nature. 575:366. PubMed Park PW, et al. 2018. Methods Cell Biol. 143:317. PubMed Cui X, et al. 2017. J Immunol. 199:4066. PubMed Platteel ACM, et al. 2018. Front Immunol. 1.544444444. PubMed Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed\u003cbr\u003e\nRRID: AB_10959655 (BioLegend Cat. No. 142501) AB_10965646 (BioLegend Cat. No. 142502)\u003cbr\u003e\nStructure: Transmembrane heparan sulfate proteoglycan; member of the syndecan proteoglycan family, 100-200 kD\u003cbr\u003e\nFunction: Cell adhesion, cell motility, cell migration, cell proliferation\u003cbr\u003e\nCell Type: B cells\u003cbr\u003e\nBiology Area: Apoptosis\/Tumor Suppressors\/Cell Death, Cell Adhesion, Cell Biology, Cell Motility\/Cytoskeleton\/Structure, Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Zong F, et al. 2011. PLoS ONE 6:e14816. 2. Yamashita Y, et al. 1999. J. Immunol. 162:5940. 3. Sanderson RD, et al. 1989. Cell. Regul. 1:27.\u003cbr\u003e\nGene ID: 20969\u003cbr\u003e\nUniProt: View information about CD138 on UniProt.org\u003cbr\u003e\nClone: 281-2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Syndecan-1\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860883460265,"sku":"142502","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-142502","provider":"Iright","version":"1.0","type":"link"}