{"product_id":"biolegend-152404","title":"Biolegend, 152404, FITC anti-mouse CD19 Antibody, 100μg","description":"\u003cp\u003eCD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Transfected k562 cells expressing the extracellular domain of murine CD19.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP) Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)\u003cbr\u003e\nProduct Citations: Chei S, et al. 2020. Front Nutr. 7:583186. PubMed Peng J, et al. 2023. Am J Reprod Immunol. 89:e13678. PubMed Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed Zhou R, et al. 2022. EBioMedicine. 75:103762. PubMed Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed Corral D, et al. 2022. Cell Rep. 39:110715. PubMed Wu Q, et al. 2023. Cell Rep. 42:112057. PubMed Gon Y, et al. 2023. PLoS One. 18:e0279389. PubMed Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed Miller CM, et al. 2020. J Virol. 94:00:00. PubMed Hu HJ, et al. 2020. Cell Death Dis. 1.168055556. PubMed Zhao J, et al. 2019. Nat Commun. 10:899. PubMed Suzuki Y, et al. 2022. Mol Ther Nucleic Acids. 30:226. PubMed Liang Y, et al. 2020. J Immunol. 204:2984. PubMed Molina-Sanchez P, et al. 2020. Gastroenterology. 2203:159. PubMed Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed Ostendorf BN, et al. 2020. Nat Med. 26:1048. PubMed Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed Jassinskaja M, et al. 2021. Cell Reports. 34(12):108894. PubMed Cha SE, et al. 2021. Oncoimmunology. 10:1899469. PubMed Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed Deng M, et al. 2020. Nat Commun. 11:2193. PubMed Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed Tavazoie MF, et al. 2018. Cell. 172:825. PubMed Zhou G, et al. 2019. FASEB J. 33:11396. PubMed Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed Niderla-Bielinska J, et al. 2021. Int J Mol Sci. :22. PubMed Dong X, et al. 2022. Front Immunol. 13:896472. PubMed Gomzikova MO, et al. 2020. Pharmaceutics. 12:00. PubMed Silva HM, et al. 2019. J Exp Med. 216:786. PubMed Tanegashima K et al. 2017. EBioMedicine. 24:247-256 . PubMed Whiteley AM et al. 2017. eLife. 6 pii: e26435. PubMed Jiang W, et al. 2021. Cell Rep. 37:110112. PubMed\u003cbr\u003e\nRRID: AB_2629812 (BioLegend Cat. No. 152403) AB_2629813 (BioLegend Cat. No. 152404)\u003cbr\u003e\nStructure: Ig superfamily, associates with CD21 and CD81, 95 kD.\u003cbr\u003e\nDistribution: Pro-B cells to mature B cells (during development), follicular dendritic cells.\u003cbr\u003e\nFunction: Modulates B cell activation and differentiation.\u003cbr\u003e\nLigand\/Receptor: CD21, CD81, Leu-13.\u003cbr\u003e\nCell Type: B cells, Dendritic cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341. 2. Krop I, et al. 1996. Eur. J. Immunol. 26:238. 3. Krop I, et al. 1996. J. Immunol. 157:48. 4. Tedder TF, et al. 1994. Immunol. Today 15:437.\u003cbr\u003e\nGene ID: 12478\u003cbr\u003e\nUniProt: View information about CD19 on UniProt.org\u003cbr\u003e\nClone: 1D3\/CD19\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: B4, CVID3\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860851478697,"sku":"152404","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-152404","provider":"Iright","version":"1.0","type":"link"}