{"product_id":"biolegend-152410","title":"Biolegend, 152410, APC anti-mouse CD19 Antibody, 100μg","description":"\u003cp\u003eCD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Transfected k562 cells expressing the extracellular domain of murine CD19.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 0.2 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: blocking1,2 and immunoprecipitation1.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Krop I, et al. 1996. Eur. J. Immunol. 26:238. (FC, Blocking, IP) Abraham P, et al. 2014. Clin. Exp. Immunol. 175:181. (Blocking)\u003cbr\u003e\nProduct Citations: Xing J, et al. 2021. Cell Reports. 35(12):109205. PubMed Lin J, et al. 2022. Adv Sci (Weinh). 9:e2202633. PubMed Rahman SMT, et al. 2022. Cell Rep. 41:111682. PubMed Pan Y, et al. 2023. Adv Sci (Weinh). 10:e2206792. PubMed Gu J, et al. 2023. J Cell Biochem. 124:557. PubMed Ma X, et al. 2023. Nat Commun. 14:1606. PubMed Thomas R, et al. 2021. Immunology. 163:478. PubMed Ali LR, et al. 2023. J Exp Med. 220: . PubMed Fachi JL et al. 2019. Cell reports. 27(3):750-761 . PubMed Prystaz K, et al. 2018. Am J Pathol. 188:474. PubMed Thompson PJ et al. 2019. Cell metabolism. 29(5):1045-1060 . PubMed Hering L, et al. 2021. Int J Mol Sci. 22:. PubMed Dignum T, et al. 2021. Cell Rep. 36:109675. PubMed Tu X, et al. 2022. Nat Commun. 13:6977. PubMed Liang Z, et al. 2020. Pain. 161:2089. PubMed Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed Zhang F, et al. 2019. Immunity. 50:738. PubMed Chen C, et al. 2019. Cell Rep. 29:4200. PubMed Frazier T, et al. 2018. Adipocyte. 0.41875. PubMed Haase C, et al. 2022. Nat Methods. 19:1622. PubMed Bonglack EN, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed Leal AS, et al. 2019. Sci Rep. 5.286111111. PubMed Ercoli G, et al. 2022. Clin Transl Immunology. 11:e1366. PubMed Wang X, et al. 2018. Cell Death Dis. 9:578. PubMed Li H, et al. 2019. Front Immunol. 2.205555556. PubMed Oka Y, et al. 2020. Sci Adv. 6:. PubMed Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed Nordin F, et al. 2020. BMC Pregnancy and Childbirth. 20(1):399. PubMed Li E, et al. 2021. Front Immunol. 12:667177. PubMed Tuong ZK, et al. 2021. Cell Rep. 37:110132. PubMed Thürmer M, et al. 2022. Nat Commun. 13:2982. PubMed Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed Lee A, et al. 2022. Nat Commun. 13:549. PubMed Chonwerawong M, et al. 2020. Gastroenterology. 159:169. PubMed Spath S, et al. 2022. iScience. 25:104998. PubMed\u003cbr\u003e\nRRID: AB_2629838 (BioLegend Cat. No. 152409) AB_2629839 (BioLegend Cat. No. 152410)\u003cbr\u003e\nStructure: Ig superfamily, associates with CD21 and CD81, 95 kD.\u003cbr\u003e\nDistribution: Pro-B cells to mature B cells (during development), follicular dendritic cells.\u003cbr\u003e\nFunction: Modulates B cell activation and differentiation.\u003cbr\u003e\nLigand\/Receptor: CD21, CD81, Leu-13.\u003cbr\u003e\nCell Type: B cells, Dendritic cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341. 2. Krop I, et al. 1996. Eur. J. Immunol. 26:238. 3. Krop I, et al. 1996. J. Immunol. 157:48. 4. Tedder TF, et al. 1994. Immunol. Today 15:437.\u003cbr\u003e\nGene ID: 12478\u003cbr\u003e\nUniProt: View information about CD19 on UniProt.org\u003cbr\u003e\nClone: 1D3\/CD19\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: B4, CVID3\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860851642537,"sku":"152410","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-152410","provider":"Iright","version":"1.0","type":"link"}