{"product_id":"biolegend-156604","title":"Biolegend, 156604, TruStain FcX™ PLUS (anti-mouse CD16\/32) Antibody, 500μg","description":"\u003cp\u003eCD16 is the low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16\/CD32 are expressed on B cells, monocytes\/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses. TruStain FcX™ PLUS is specific to the common epitope of CD16\/CD32. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors and is more effective than TruStain FcX™.\u003cbr\u003e\n500μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nPurity: The antibody was purified by affinity chromatography.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The CD16\/32 antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with TruStain FcX™ PLUS for 5-10 minutes, on ice, at 0.25 µg per 106 cells in a volume of 100 µl, prior to immunostaining. It is not necessary to wash the cells between the blocking and immunostaining steps.\u003cbr\u003e\nApplication Notes: Clone S17011E blocks both clone 93 and 2.4G2 also raised against mouse CD16\/32\u003cbr\u003e\nProduct Citations: Sugitani N, et al. 2022. Cell Rep. 40:111371. PubMed Gonzalez C, et al. 2022. Life Sci. 309:121003. PubMed Egli J, et al. 2022. MAbs. 14:2143009. PubMed Cai Z, et al. 2023. Adv Sci (Weinh). 10:e2207155. PubMed Li T, et al. 2023. Adv Sci (Weinh). 10:e2206517. PubMed Liu HJ, et al. 2023. Nat Commun. 14:1214. PubMed Sang H, et al. 2023. Adv Clin Exp Med. 32:551. PubMed Zyla-Jackson K, et al. 2023. Front Neurol. 14:1113954. PubMed Chen Y, et al. 2023. J Nanobiotechnology. 21:98. PubMed Gao X, et al. 2023. Front Immunol. 14:1142428. PubMed Zhou Y, et al. 2023. NPJ Regen Med. 8:23. PubMed Barisas DAG, et al. 2023. PLoS Biol. 21:e3001746. PubMed Lee K, et al. 2023. JCI Insight. 8:. PubMed Lin W, et al. 2023. Commun Biol. 6:447. PubMed Miyake K, et al. 2023. 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STAR Protoc. 3:101464. PubMed\u003cbr\u003e\nRRID: AB_2783137 (BioLegend Cat. No. 156603) AB_2783138 (BioLegend Cat. No. 156604)\u003cbr\u003e\nStructure: Ig superfamily, 40-60 kD\u003cbr\u003e\nDistribution: B cells, monocyte\/macrophages, NK cells, neutrophils, mast cells, dendritic cells\u003cbr\u003e\nLigand\/Receptor: IgG\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Fc Receptors\u003cbr\u003e\nGene ID: 1413014131\u003cbr\u003e\nUniProt: View information about CD16\/32 on UniProt.org\u003cbr\u003e\nClone: S17011E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD16, CD32\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866231034025,"sku":"156604","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-156604","provider":"Iright","version":"1.0","type":"link"}