{"product_id":"biolegend-161302","title":"Biolegend, 161302, Purified anti-mouse PD-1H (VISTA) Antibody, 100μg","description":"\u003cp\u003ePD-1H, also known as VISTA, is a 309 aa type I transmembrane protein, composed of seven exons. PD-1H has one Ig-V like domain, and its sequence is similar to the Ig-V domains of the members of CD28 and B7 families. PD-1H is expressed by a subset of T cells, macrophages, dendritic cells, neutrophils, and NK cells. It has been proposed that PD-1H can be useful to modulate the host immune response to allogeneic transplants.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Recombinant mouse VISTA\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: IHC-F - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a concentration range of 5.0 - 10 µg\/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2876577 (BioLegend Cat. No. 161302)\u003cbr\u003e\nStructure: Type I transmembrane protein, member of the CD28 family\u003cbr\u003e\nDistribution: Macrophages, dendritic cells, neutrophils, NK cells, naïve and activated T cells\u003cbr\u003e\nFunction: Negative regulator of the immune response\u003cbr\u003e\nInteraction: Dendritic cells, Macrophages, Neutrophils, NK cells, T cells\u003cbr\u003e\nCell Type: Dendritic cells, Macrophages, Neutrophils, NK cells, T cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nAntigen References: Flies DB, et al. 2011. J Immunol. 187:1537-41. Wang Li, et al. 2011. J Exp Med. 208:577-92.\u003cbr\u003e\nGene ID: 74048\u003cbr\u003e\nUniProt: View information about PD-1H on UniProt.org\u003cbr\u003e\nClone: A17207D\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: PD-1 homolog, Dies1, B7-H5\u003cbr\u003e\nIsotype: Rat IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866057658537,"sku":"161302","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-161302","provider":"Iright","version":"1.0","type":"link"}