{"product_id":"biolegend-163902","title":"Biolegend, 163902, Purified anti-mouse CD182 (CXCR2) Antibody, 100μg","description":"\u003cp\u003eCD182, also known as CXCR2, is a G-protein coupled receptor with 7 transmembrane regions that is involved in chemotaxis, neutrophil activation and angiogenesis. CXCR2 is expressed by neutrophils, basophils, subset of T cells, monocytes, macrophages, NK and NKT cells. Its ligands are CXCL1, CXCL2, CXCL3 and CXCL5.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Pre-B cell transfected with mCXCR2\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested Block - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone 3F10-B3 blocks the chemotaxis towards CXCR2 ligands.\u003cbr\u003e\nRRID: AB_2924493 (BioLegend Cat. No. 163902)\u003cbr\u003e\nStructure: G-protein coupled receptor, 7 transmembrane regions.\u003cbr\u003e\nDistribution: Neutrophils, basophils, subset of T cells, monocytes, macrophages, and natural killer cells (NK)\u003cbr\u003e\nFunction: Chemotaxis, neutrophil activation, and angiogenesis\u003cbr\u003e\nLigand\/Receptor: CXCL1, CXCL2, CXCL3, and CXCL5\u003cbr\u003e\nCell Type: Neutrophils\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules, Cytokine\/Chemokine Receptors, GPCR\u003cbr\u003e\nAntigen References: Spaan AN, et al. 2014. Nat Commun. 5:5438. Natsuaki Y, et al. 2014. Nat. Immunol. 11:1064-9. Hsieh CY, et al. 2014. J Immunol. 193:3693-703.\u003cbr\u003e\nGene ID: 12765\u003cbr\u003e\nUniProt: View information about CD182 on UniProt.org\u003cbr\u003e\nClone: 3F10-B3\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-8RB, GRO\/MGSA, Cmkar2\u003cbr\u003e\nIsotype: Mouse IgG2c, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862395310249,"sku":"163902","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-163902","provider":"Iright","version":"1.0","type":"link"}