{"product_id":"biolegend-168602","title":"Biolegend, 168602, Purified anti-mouse CMKLR1 Antibody, 100μg","description":"\u003cp\u003eCMKLR1 (chemerin chemokine-like receptor1), also know as DEZ or ChemR23, is a ~42 kD G-protein coupled receptor. CMKLR1 is expressed on differentiated adipocytes, dendritic cells, macrophages, and NK cells. It was reported to bind to chemerin which acts as a chemoattractant for dendritic cells and macrophages to inflammatory regions. CMKLR1 is also believed to be involved with adipose tissue homeostasis or adipose tissue metabolism.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: Mouse CMKLR1 N-terminal peptide\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_3717215 (BioLegend Cat. No. 168602)\u003cbr\u003e\nStructure: G-protein coupled receptor, seven-transmembrane domain structure\u003cbr\u003e\nDistribution: DCs, macrophages, NK cells, neutrophils and adipocytes\u003cbr\u003e\nFunction: Chemoattractant for dendritic cells and macrophages to inflammatory regions. Involved with adipose tissue homeostasis and metabolism.\u003cbr\u003e\nInteraction: G proteins\u003cbr\u003e\nLigand\/Receptor: Chemerin, Resolvin E1\u003cbr\u003e\nCell Type: Dendritic cells, Macrophages\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Cytokine\/Chemokine Receptors\u003cbr\u003e\nAntigen References: Methner A, et al. 1997. Biochem Biophys Res Commun. 17:336. Parmentier M, et al. 1998. Eur J Immunol. 28:1689. Zabel BA, et al. 2006. Exp Hematology. 34:1106. Rouger L, et al. 2013. J.Endocrinology. 219:279.\u003cbr\u003e\nGene ID: 14747\u003cbr\u003e\nUniProt: View information about CMKLR1 on UniProt.org\u003cbr\u003e\nClone: S22029A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: DEZ, ERV1, RVER1, ChemR23, CML1, GPCR27\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866277597353,"sku":"168602","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-168602","provider":"Iright","version":"1.0","type":"link"}