{"product_id":"biolegend-260468","title":"Biolegend, 260468, GMP FITC anti-human CD79a (Igα) Antibody, 100tests","description":"\u003cp\u003eCD79a is a 47 kD type I integral membrane protein, also known as mb-1 or Iga. It is a member of the Ig superfamily and disulphide-associated with CD79b (B29). The interaction of CD79a\/CD79b heterodimer with B cell suface Ig forms B cell antigen receptor complex. CD79a is expressed in B cells from early pre-B to plasma cell stage. It has been shown that CD79a is also weakly expressed in some precursors of T- and myeloid cells. CD79 mediates the transport of IgM to B cell surface and transduces signals initiated by BCR aggregation.\u003cbr\u003e\n100tests\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w\/v) BSA (origin USA) and a stabilizer\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 140 µg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: ICFC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nDisclaimer: GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include: Batch-to-batch consistency Material traceability Documented procedures Documented employee training Equipment maintenance and monitoring records Lot-specific certificates of analysis Quality audits per ISO 13485:2016 QA review of released products\u003cbr\u003e\nStructure: 47 kD, type I integral protein, Ig superfamily, CD79a\/CD79b heterodimer interacts with B cell membrane Ig.\u003cbr\u003e\nDistribution: B cells (from early pre-B to plasma cell stage), some T and myeloid cell precursors\u003cbr\u003e\nFunction: In association with CD79b and B cell membrane Ig to form B cell antigen receptor complex\u003cbr\u003e\nCell Type: B cells, Hematopoietic stem and progenitors\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Zola Heddy, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD markers. WILEY-LISS 2. Astsaturov IA, et al. 1996. Leukemia 10:769 3. Mson DY, et al. 1995 Blood 86:1453 4. Hashimoto M, et al. 2002. J. Pathol. 197:341\u003cbr\u003e\nGene ID: 973\u003cbr\u003e\nUniProt: View information about CD79a on UniProt.org\u003cbr\u003e\nClone: HM47\u003cbr\u003e\nWorkshop: V cB017\u003cbr\u003e\nOther Names: Mb-1, Iga, CD79\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866524438697,"sku":"260468","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-260468","provider":"Iright","version":"1.0","type":"link"}