{"product_id":"biolegend-260496","title":"Biolegend, 260496, GMP FITC anti-human TCR α\/β Antibody, 100tests","description":"\u003cp\u003eThe IP26 antibody reacts with a monomorphic determinant of the α\/β T-cell receptor, which is expressed on greater than 95% of normal peripheral blood CD3 + T cells. The α\/β TCR recognizes a peptide bound to MHC leading to T-cell activation.\u003cbr\u003e\n100tests\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w\/v) BSA (origin USA) and a stabilizer\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: 400 µg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: T cell activation. When co-staining with anti-CD3, we recommend using clone UCHT1, since we have confirmed that IP26 does not compete with this clone. Other anti-CD3 clones may compete out the binding of IP26.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. (FC) Joseph A, et al. 2008. J. Virol. 82:3078. (FC) PubMed Pinto JP, et al. 2010. Immunology. 130:217. PubMed\u003cbr\u003e\nDisclaimer: GMP RUO Flow Cytometry Antibodies. BioLegend GMP RUO fluorophore conjugated antibodies are manufactured in a dedicated GMP facility and compliant with ISO 13485:2016. For research use only. Not for use in diagnostic or therapeutic procedures. Our processes include: Batch-to-batch consistency Material traceability Documented procedures Documented employee training Equipment maintenance and monitoring records Lot-specific certificates of analysis Quality audits per ISO 13485:2016 QA review of released products\u003cbr\u003e\nStructure: Ig superfamily, with CD3 forms CD3\/TCR complex\u003cbr\u003e\nDistribution: T cells, thymocytes\u003cbr\u003e\nFunction: Antigen recognition, T cell activation\u003cbr\u003e\nLigand\/Receptor: Peptide bound to MHC\u003cbr\u003e\nCell Type: T cells, Thymocytes, Tregs\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Marchalonis J, et al. 2002. J. Mol. Recognit. 15:260.\u003cbr\u003e\nGene ID: 69556957\u003cbr\u003e\nUniProt: View information about TCR alpha\/beta on UniProt.org\u003cbr\u003e\nClone: IP26\u003cbr\u003e\nOther Names: α\/β TCR, TCR α\/β\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866524864681,"sku":"260496","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-260496","provider":"Iright","version":"1.0","type":"link"}