{"product_id":"biolegend-309602","title":"Biolegend, 309602, Purified anti-human CD38 Recombinant Antibody, 100μg","description":"\u003cp\u003eCD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: QA19A33 clone of antibody is able to completely block the binding of clone HB-7 to CD38.\u003cbr\u003e\nRRID: AB_2890744 (BioLegend Cat. No. 309602)\u003cbr\u003e\nStructure: ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD\u003cbr\u003e\nDistribution: T cells, B cells, NK-cells, myeloid, plasma, and dendritic cells\u003cbr\u003e\nFunction: Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation\u003cbr\u003e\nLigand\/Receptor: CD31, hyaluronic acid\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Leukemia, Leukocytes, Plasma cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151. 2. Lund F, et al. 1995. Immunol. Today 16:469.\u003cbr\u003e\nGene ID: 952\u003cbr\u003e\nUniProt: View information about CD38 on UniProt.org\u003cbr\u003e\nClone: QA19A36\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: HB7, T10, ADP-ribosyl cyclase\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866188370089,"sku":"309602","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-309602","provider":"Iright","version":"1.0","type":"link"}