{"product_id":"biolegend-326308","title":"Biolegend, 326308, PE anti-human CD252 (OX40L) Antibody, 100tests","description":"\u003cp\u003eOX40 ligand (OX40L) is a 35 kD type II transmembrane protein which belongs to TNF superfamily, also known as gp34, CD252, CD134L or TNFSF4. The OX40 ligand is expressed on activated B cells, activated endothelial cells, mature dendritic cells, activated CTLs, activated mast cells, and airway smooth muscle cells. OX40 ligand interacts with OX40 antigen (CD134) expressed predominantly on activated T cells to regulate T cell proliferation and differentiation, and to enhance immunoglobulin secretion by activated B cells.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nProduct Citations: Castellanos JG et al. 2018. Immunity. 49(6):1077-1089 . PubMed Gajdasik DW, et al. 2020. Nat Commun. 2.834027778. PubMed Liang Y, et al. 2019. J Allergy Clin Immunol. 144:1025. PubMed Guo M, et al. 2021. Front Oncol. 11:632540. PubMed Valenzuela NM, et al. 2021. Front Immunol. 12:648946. PubMed Halim TYF et al. 2018. Immunity. 48(6):1195-1207 . PubMed\u003cbr\u003e\nRRID: AB_2207272 (BioLegend Cat. No. 326307) AB_2207271 (BioLegend Cat. No. 326308)\u003cbr\u003e\nStructure: NGF\/TNF superfamily, 35 kD\u003cbr\u003e\nDistribution: Activated B cells, activated endothelial cells, mature dendritic cells, airway smooth muscle cells\u003cbr\u003e\nFunction: B-cell\/T-cell interaction, costimulation\u003cbr\u003e\nLigand\/Receptor: OX40 (CD134)\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Endothelial cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Immune Checkpoint Receptors\u003cbr\u003e\nAntigen References: 1. Imura A, et al. 1996. J. Exp. Med. 183:2185. 2. Ohshima Y, et al. 1997. J. Immunol. 159:3838. 3. Ito T, et al. 2005. J. Exp.Med. 202:1213. 4. Ito T, et al. 2006. Proc. Natl. Acad.Sci. USA. 103:13138.\u003cbr\u003e\nGene ID: 7292\u003cbr\u003e\nUniProt: View information about CD252 on UniProt.org\u003cbr\u003e\nClone: 11C3.1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Gp34, OX40L, CD134L, CD252, TNFSF4\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46860792856745,"sku":"326308","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-326308","provider":"Iright","version":"1.0","type":"link"}