{"product_id":"biolegend-328501","title":"Biolegend, 328501, Purified anti-human CD102 (ICAM-2) Antibody, 25μg","description":"\u003cp\u003eCD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a\/CD18), DC-SIGN and MAC-1.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus, Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: ICAM-2 cDNA transfected COS cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested IP, IHC-F - Reported in the literature, not verified in house\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Additional reported applications: immunoprecipitation(1), blocking the interaction between ICAM-2 and LFA-1(1), immunohistochemical staining(2) of frozen tissue sections\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): DeFougerolles AR,et al.1991.J. Exp.Med.174:253. Van Herpen CML,et al.2005.Clin. Cancer Res.11:1899\u003cbr\u003e\nProduct Citations: Kim N, et al. 2020. Cancers (Basel). 12:. PubMed\u003cbr\u003e\nRRID: AB_1134245 (BioLegend Cat. No. 328502)\u003cbr\u003e\nStructure: 55 kD type I transmembrane glycoprotein, Ig superfamily\u003cbr\u003e\nDistribution: Vascular endothelial cells, lymphocytes, monocytes, platelets\u003cbr\u003e\nFunction: Adhesion, costimulation\u003cbr\u003e\nLigand\/Receptor: LFA-1, DC-SIGN, MAC-1\u003cbr\u003e\nCell Type: Endothelial cells, Lymphocytes, Monocytes, Platelets\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1.Weber KSC, et al.2004.Inflammation.28:177. 2.Barclay A, et al.1997 The Leukoycte Antigen FactsbookAcademic Press. 3. Casasnovas JM, et al.1999.P. Natl. Acad. Sci. USA96:3017. 4. Diamonds MS, et al.1990. J. Cell Biol.111:3129.\u003cbr\u003e\nGene ID: 3384\u003cbr\u003e\nUniProt: View information about CD102 on UniProt.org\u003cbr\u003e\nClone: CBR-IC2\/2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: V BP363\u003cbr\u003e\nOther Names: Intercellular Adhesion Molecule-2, ICAM-2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862970224809,"sku":"328501","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-328501","provider":"Iright","version":"1.0","type":"link"}