{"product_id":"biolegend-331015","title":"Biolegend, 331015, PerCP\/Cyanine5.5 anti-human CD101 (BB27) Antibody, 25tests","description":"\u003cp\u003eCD101 is a type I transmembrane glycoprotein, known as V7, and P126. It is a 120 kD homodimer, the member of EWI family within Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs posses higher inhibitory function. The biological function of CD101 is still not clear. But it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus, Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PerCP\/Cyanine5.5 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.* PerCP\/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Gouttefangeas C, et al. 1994. Int. Immunol. 6:423 Bouloc A, et al. 2000. Histopathology. 36:229\u003cbr\u003e\nProduct Citations: Harper JL, et al. 2020. Nat Med. 519:26. PubMed\u003cbr\u003e\nRRID: AB_2716110 (BioLegend Cat. No. 331015) AB_2716111 (BioLegend Cat. No. 331016)\u003cbr\u003e\nStructure: Type I transmembrane glycoprotein, homodimer, Ig superfamily, 120 kD\u003cbr\u003e\nDistribution: Monocytes, granulocytes, dendritic cells, T cell subset and activated T cells\u003cbr\u003e\nCell Type: Dendritic cells, Granulocytes, Monocytes, T cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nAntigen References: 1. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley \u0026amp; Sons Inc, Publication 2. Bagot M, et al. 1997. Tissue Antigen 50:439\u003cbr\u003e\nGene ID: 9398\u003cbr\u003e\nUniProt: View information about CD101 on UniProt.org\u003cbr\u003e\nClone: BB27\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: V T040\u003cbr\u003e\nOther Names: V7, P126\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: How stable is PerCP\/Cyanine5.5 tandem as compared to PerCP alone?\u003cbr\u003e\nA: PerCP\/Cyanine5.5 is quite photostable and also better than PerCP alone in withstanding fixation.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862900756649,"sku":"331015","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-331015","provider":"Iright","version":"1.0","type":"link"}