{"product_id":"biolegend-331404","title":"Biolegend, 331404, Biotin anti-human TCR Vδ2 Antibody, 100μg","description":"\u003cp\u003eThe Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ\/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ\/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ\/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Chimpanzee\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Rojas RE, et al. 2005. J. Infect. Dis. 192:1806. Correia DV, et al. 2011. Blood 118:992. (FC) PubMed\u003cbr\u003e\nProduct Citations: Ferry GM, et al. 2022. Front Immunol. 13:863155. PubMed Keller B, et al. 2016. J Exp Med. 213: 1185 - 1199. PubMed\u003cbr\u003e\nRRID: AB_1089228 (BioLegend Cat. No. 331404)\u003cbr\u003e\nStructure: Ig superfamily member, TCR γ\/δ with CD3 forms the CD3\/TCR complex\u003cbr\u003e\nDistribution: Expressed on majority of peripheral γ\/δT cells\u003cbr\u003e\nFunction: Antigen recognition, T cell activation\u003cbr\u003e\nLigand\/Receptor: Peptide bound to MHC\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Scotet E, et al. 2005. Immunity 22:71. 2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144.\u003cbr\u003e\nGene ID: 6964\u003cbr\u003e\nUniProt: View information about TCR Vdelta2 on UniProt.org\u003cbr\u003e\nClone: B6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor V δ 2, TRDV2, TCRDV102S1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: How many biotin molecules are per antibody structure?\u003cbr\u003e\nA: We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862894301353,"sku":"331404","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-331404","provider":"Iright","version":"1.0","type":"link"}