{"product_id":"biolegend-331420","title":"Biolegend, 331420, APC\/Fire™ 750 anti-human TCR Vδ2 Antibody, 100tests","description":"\u003cp\u003eThe Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ\/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ\/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ\/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Chimpanzee\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC\/Fire™ 750 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * APC\/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Rojas RE, et al. 2005. J. Infect. Dis. 192:1806. Correia DV, et al. 2011. Blood 118:992. (FC) PubMed\u003cbr\u003e\nProduct Citations: Ogishi M, et al. 2023. J Exp Med. 220: . PubMed Rosain J, et al. 2023. Cell. 186:621. PubMed Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed\u003cbr\u003e\nRRID: AB_2687325 (BioLegend Cat. No. 331419) AB_2687326 (BioLegend Cat. No. 331420)\u003cbr\u003e\nStructure: Ig superfamily member, TCR γ\/δ with CD3 forms the CD3\/TCR complex\u003cbr\u003e\nDistribution: Expressed on majority of peripheral γ\/δT cells\u003cbr\u003e\nFunction: Antigen recognition, T cell activation\u003cbr\u003e\nLigand\/Receptor: Peptide bound to MHC\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Scotet E, et al. 2005. Immunity 22:71. 2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144.\u003cbr\u003e\nGene ID: 6964\u003cbr\u003e\nUniProt: View information about TCR Vdelta2 on UniProt.org\u003cbr\u003e\nClone: B6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor V δ 2, TRDV2, TCRDV102S1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862893940905,"sku":"331420","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-331420","provider":"Iright","version":"1.0","type":"link"}