{"product_id":"biolegend-331428","title":"Biolegend, 331428, Brilliant Violet 421™ anti-human TCR Vδ2 Antibody, 100tests","description":"\u003cp\u003eThe Vδ2 TCR is a variant of the TCR δ chain expressed on a subset of γ\/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ\/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ\/δ TCR is an heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: Chimpanzee\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450\/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd. Learn more about Brilliant Violet™. This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Rojas RE, et al. 2005. J. Infect. Dis. 192:1806. Correia DV, et al. 2011. Blood 118:992. (FC) PubMed\u003cbr\u003e\nRRID: AB_2783210 (BioLegend Cat. No. 331427) AB_2783211 (BioLegend Cat. No. 331428)\u003cbr\u003e\nStructure: Ig superfamily member, TCR γ\/δ with CD3 forms the CD3\/TCR complex\u003cbr\u003e\nDistribution: Expressed on majority of peripheral γ\/δT cells\u003cbr\u003e\nFunction: Antigen recognition, T cell activation\u003cbr\u003e\nLigand\/Receptor: Peptide bound to MHC\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Scotet E, et al. 2005. Immunity 22:71. 2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144.\u003cbr\u003e\nGene ID: 6964\u003cbr\u003e\nUniProt: View information about TCR Vdelta2 on UniProt.org\u003cbr\u003e\nClone: B6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: T cell receptor V δ 2, TRDV2, TCRDV102S1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What is the F\/P ratio range of our BV421™ format antibody reagents?\u003cbr\u003e\nA: It is lot-specific. On average it ranges between 2-4.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862894399657,"sku":"331428","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-331428","provider":"Iright","version":"1.0","type":"link"}