{"product_id":"biolegend-332405","title":"Biolegend, 332405, FITC anti-human CD35 Antibody, 25tests","description":"\u003cp\u003eCD35 is a type I single chain of glycoprotein, also known as C3b\/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC- Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nProduct Citations: Mannes M, et al. 2023. J Innate Immun. 412:15. PubMed Wohlgemuth L, et al. 2022. Cells. 11: . PubMed\u003cbr\u003e\nRRID: AB_2890766 (BioLegend Cat. No. 332405) AB_2890766 (BioLegend Cat. No. 332406)\u003cbr\u003e\nDistribution: B cells, Dendritic cells, Erythrocytes, Granulocytes, Monocytes, NK cells, T cells\u003cbr\u003e\nFunction: Adhesion, mediate phagocytosis, inhibit T-cell proliferation\u003cbr\u003e\nLigand\/Receptor: C3b, iC3, C4b, iC4\u003cbr\u003e\nCell Type: B cells, Dendritic cells, Erythrocytes, Granulocytes, Monocytes, NK cells, T cells\u003cbr\u003e\nBiology Area: Cell Biology, Complement, Immunology, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Vorup-Jensen et al. 2018. Front Immunol. 9:2716. 2. Ogembo et al. 2013. Cell Rep. 3(2):371-85.\u003cbr\u003e\nGene ID: 1378\u003cbr\u003e\nUniProt: View information about CD35 on UniProt.org\u003cbr\u003e\nClone: 9H3\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: C3b\/C4b receptor, complement receptor type 1 (CR1)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862514585769,"sku":"332405","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-332405","provider":"Iright","version":"1.0","type":"link"}