{"product_id":"biolegend-334402","title":"Biolegend, 334402, Purified anti-human CD245 (p220\/240) Antibody, 100μg","description":"\u003cp\u003eCD245 is a 220-250 kD transmembrane glycoprotein, also known as p220\/240, DY12 or DY35. It is expressed on peripheral blood lymphocytes, monocytes, granulocytes, and platelets. The expression level of CD245 on lymphocytes can be upregulated after 3-7 days stimulation with PHA. It has been reported that CD245 is involved in signal transduction and costimulation of T and NK cells.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_1186022 (BioLegend Cat. No. 334402)\u003cbr\u003e\nDistribution: Blood lymphocytes, monocytes and granulocytes\u003cbr\u003e\nFunction: Signal transduction and costimulation\u003cbr\u003e\nCell Type: Granulocytes, Lymphocytes, Monocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. H. Zola et al. Eds. 2007. Leukocyte and Stromal Cell Molecule:The CD Markers. WILEY-LISS:A John Wiley \u0026amp; Sons Inc, Publication\u003cbr\u003e\nGene ID: 4863\u003cbr\u003e\nUniProt: View information about CD245 on UniProt.org\u003cbr\u003e\nClone: DY12\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: P220\/240, DY12, DY35\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46863063711913,"sku":"334402","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-334402","provider":"Iright","version":"1.0","type":"link"}