{"product_id":"biolegend-336220","title":"Biolegend, 336220, APC\/Fire™ 750 anti-human CD36 Antibody, 100tests","description":"\u003cp\u003eCD36 is an 85 kD integral membrane glycoprotein, also known as GPIIIb, or GPIV. It is expressed on various epithelial and endothelial cells as well as erythrocytes, platelets, macrophages\/monocytes and some macrophage-derived dendritic cells. CD36 functions as a scavenger receptor, binding thrombospondin, long chain fatty acids, oxidized LDL, collagen type I, IV, and V as well as apoptotic cells. The 5-271 antibody has been reported to be useful for flow cytometry.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human platelets\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC\/Fire™ 750 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. * APC\/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats) include: immunofluorescence2.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Stelner E, et al. 2006. J. Cell Sci. 119:459. Stewart DA, et al. 2012. Mol. Cancer Res. 10:727. (IF)\u003cbr\u003e\nProduct Citations: Hofbauer D, et al. 2021. Immunity. 54(8):1772-1787.e9. PubMed Herati RS, et al. 2022. Nat Immunol. 23:1183. PubMed\u003cbr\u003e\nRRID: AB_2629775 (BioLegend Cat. No. 336219) AB_2629776 (BioLegend Cat. No. 336220)\u003cbr\u003e\nStructure: Integral membrane protein, CD36 family, single chain glycoprotein, 85-113 kD\u003cbr\u003e\nDistribution: Expressed in various epithelial and endothelial cells, erythrocytes, platelets, monocytes\/ macrophages, some macrophage-derived dendritic cells\u003cbr\u003e\nFunction: Scavenger receptor for thrombospondin, long chain fatty acids, anionic phospholipids, oxidized LDL, collagen types I, IV and V. Involved in recognition and phagocytosis of apoptotic cells, cell adhesion.\u003cbr\u003e\nLigand\/Receptor: Thrombospondin, anionic phospholipids, oxidized LDL, collage types I, IV, and V\u003cbr\u003e\nCell Type: Dendritic cells, Endothelial cells, Epithelial cells, Erythrocytes, Macrophages, Monocytes, Platelets\u003cbr\u003e\nBiology Area: Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Hogg N, et al. 1984. Immunology 53-753. 2. Greenwalt DE, et al. 1992. Blood 80:1105. 3. Armsesilla AL, et al.1994. J. Biol. Chem. 269:18985. 4. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.\u003cbr\u003e\nGene ID: 948\u003cbr\u003e\nUniProt: View information about CD36 on UniProt.org\u003cbr\u003e\nClone: 5-271\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: GPIIIb, GPIV\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862422081705,"sku":"336220","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-336220","provider":"Iright","version":"1.0","type":"link"}