{"product_id":"biolegend-366110","title":"Biolegend, 366110, PE\/Cyanine7 anti-human EMR3 Recombinant Antibody, 100tests","description":"\u003cp\u003eEMR3 is a member of the EGF-7 transmembrane (TM7) adhesion GPCR family. It is predominantly expressed on granulocytes, neutrophils, monocytes, and macrophages, and at lower levels on mature myeloid cells and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors.  Studies suggest that the EMR3 molecule is upregulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. EMR3 may play a role in myeloid-myeloid interactions during immune and inflammatory responses.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2936706 (BioLegend Cat. No. 366109) AB_2936706 (BioLegend Cat. No. 366110)\u003cbr\u003e\nStructure: EGF-like domain, 7-transmembrane\u003cbr\u003e\nDistribution: Granulocytes, neutrophils, monocytes, macrophages, dendritic cells\u003cbr\u003e\nFunction: Adhesion, myeloid-myeloid cell interaction\u003cbr\u003e\nCell Type: Dendritic cells, Granulocytes, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Adaptive Immunity, Cell Adhesion, Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Adhesion Molecules, GPCR\u003cbr\u003e\nAntigen References: Matmati M. et al. 2007, J Leukoc Biol. 81:440-8. Stacey M, et al. 2001. J Biol Chem. 276:18863-70.\u003cbr\u003e\nGene ID: 84658\u003cbr\u003e\nUniProt: View information about EMR3 on UniProt.org\u003cbr\u003e\nClone: QA20A59\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Adhesion G protein-coupled receptor E3; EGF module-containing mucin-like hormone receptor 3\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866192662697,"sku":"366110","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-366110","provider":"Iright","version":"1.0","type":"link"}