{"product_id":"biolegend-366310","title":"Biolegend, 366310, PE\/Cyanine7 anti-human CD18 Antibody, 100tests","description":"\u003cp\u003eCD18, also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin, is a 90 - 95 kD type I glycoprotein. CD18 non-covalently associates with CD11a, CD11b, or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in the adhesion and signaling in hematopoietic cells.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Purified human LFA-1\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE\/Cyanine7 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications (for the relevant formats of this clone) include: activation of LFA-1 and MAC-11,2. The LEAF™ or Ultra-LEAF™ purified antibody (Endotoxin \u0026lt; EU\/µg, Azide-Free, 0.2 µm filtered) is recommended for function assays (contact our custom solutions team).\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Petruzzelli L, et al. 1995. J. Immunol. 155:854. (Activ)Lu C, et al. 2001. J. Immunol. 166:5629. (Activ)\u003cbr\u003e\nProduct Citations: Bayik D, et al. 2022. Cancer Res. 82:4274. PubMed\u003cbr\u003e\nRRID: AB_2721657 (BioLegend Cat. No. 366309) AB_2721658 (BioLegend Cat. No. 366310)\u003cbr\u003e\nStructure: 90 - 95 kD type I transmembrane glycoprotein.\u003cbr\u003e\nDistribution: Leukocytes.\u003cbr\u003e\nFunction: Cell adhesion and signaling.\u003cbr\u003e\nInteraction: Integrin, type I transmembrane glycoprotein, associates with CD11a, CD11b, or CD11c\u003cbr\u003e\nLigand\/Receptor: ICAMs.\u003cbr\u003e\nCell Type: Leukocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175. 2. Springer TA. 1994. Cell 76:301.\u003cbr\u003e\nGene ID: 3689\u003cbr\u003e\nUniProt: View information about CD18 on UniProt.org\u003cbr\u003e\nClone: CBR LFA-1\/2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2, b2 integrin, beta 2 integrin\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862969503913,"sku":"366310","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/biolegend-366310","provider":"Iright","version":"1.0","type":"link"}